This HTML5 document contains 53 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n15http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n10http://linked.opendata.cz/resource/domain/vavai/projekt/
n11http://linked.opendata.cz/resource/domain/vavai/subjekt/
n18http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F60077344%3A_____%2F11%3A00359447%21RIV12-AV0-60077344/
n6http://linked.opendata.cz/ontology/domain/vavai/
n9http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n20http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n13http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n19http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n14http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n7http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F60077344%3A_____%2F11%3A00359447%21RIV12-AV0-60077344
rdf:type
n6:Vysledek skos:Concept
dcterms:description
The role of CD4+ and CD8+ T lymphocytes in the development of a protective immune response against Cryptosporidium muris infection was studied by the reconstitution of severe combined immunodeficient (SCID) mice with well-defined populations of either naive or immune CD8+ or CD4+ T lymphocytes. Adoptive transfer of both naive and immune CD4+ T lymphocyte subpopulations protects SCID mice against cryptosporidiosis. Moreover, a significant biological impact of activated CD8+ T cells against gastric cryptosporidiosis was observed. Thus, although CD4+ T cells are considered important in protective immunity, our results are the first to demonstrate the involvement of activated CD8+ T lymphocytes in the protection of mice against gastric cryptosporidiosis. The role of CD4+ and CD8+ T lymphocytes in the development of a protective immune response against Cryptosporidium muris infection was studied by the reconstitution of severe combined immunodeficient (SCID) mice with well-defined populations of either naive or immune CD8+ or CD4+ T lymphocytes. Adoptive transfer of both naive and immune CD4+ T lymphocyte subpopulations protects SCID mice against cryptosporidiosis. Moreover, a significant biological impact of activated CD8+ T cells against gastric cryptosporidiosis was observed. Thus, although CD4+ T cells are considered important in protective immunity, our results are the first to demonstrate the involvement of activated CD8+ T lymphocytes in the protection of mice against gastric cryptosporidiosis.
dcterms:title
Activated CD8+T cells contribute to clearance of gastric Cryptosporidium muris infections Activated CD8+T cells contribute to clearance of gastric Cryptosporidium muris infections
skos:prefLabel
Activated CD8+T cells contribute to clearance of gastric Cryptosporidium muris infections Activated CD8+T cells contribute to clearance of gastric Cryptosporidium muris infections
skos:notation
RIV/60077344:_____/11:00359447!RIV12-AV0-60077344
n6:predkladatel
n11:ico%3A60077344
n3:aktivita
n14:P n14:V n14:Z
n3:aktivity
P(KJB500960701), V, Z(AV0Z60220518)
n3:cisloPeriodika
4
n3:dodaniDat
n7:2012
n3:domaciTvurceVysledku
n15:3076210 n15:8111618 n15:3111261 n15:4228677 n15:8524777
n3:druhVysledku
n12:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
184491
n3:idVysledku
RIV/60077344:_____/11:00359447
n3:jazykVysledku
n8:eng
n3:klicovaSlova
CD4+T-lymphocytes; CD8+T-lymphocytes; Cryptosporidium muris; T-cell-mediated immunity
n3:klicoveSlovo
n13:T-cell-mediated%20immunity n13:Cryptosporidium%20muris n13:CD4%2BT-lymphocytes n13:CD8%2BT-lymphocytes
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[9D0144659169]
n3:nazevZdroje
Parasite immunology
n3:obor
n16:EC
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:projekt
n10:KJB500960701
n3:rokUplatneniVysledku
n7:2011
n3:svazekPeriodika
33
n3:tvurceVysledku
Rost, M. Salát, Jiří Sak, Bohumil Jalovecká, M. Květoňová, Dana Kváč, Martin Kodádková, Alena
n3:wos
000288249400002
n3:zamer
n9:AV0Z60220518
s:issn
0141-9838
s:numberOfPages
7
n20:doi
10.1111/j.1365-3024.2010.01271.x