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Statements

Subject Item
n2:RIV%2F60077344%3A_____%2F07%3A00084978%21RIV08-AV0-60077344
rdf:type
n8:Vysledek skos:Concept
dcterms:description
The effects of oxidative stress on adipokinetic hormone (AKH) titre in the firebug Pyrhocorris apterus were tested using paraquat (PQ). Oxidative insult resulted in enhanced protein carbonylation and a depletion of glutathione (GSH) pool in the haemolymph. Interestingly, AKH titre was significantly enhanced in haemolymph, while its content in CNS showed non-specific changes in comparable period. Co-injection of AKH with PQ reversed these effects by decreasing protein carbonyl formation, increasing reduced GSH levels, and enhancing the total antioxidant capacity of cell free plasma. Our results indicate that there is a positive feed back regulation between an oxidative stressor action and the level of AKH in insect body, and that AKHs might be involved in the activation of antioxidant protection mechanism. The effects of oxidative stress on adipokinetic hormone (AKH) titre in the firebug Pyrhocorris apterus were tested using paraquat (PQ). Oxidative insult resulted in enhanced protein carbonylation and a depletion of glutathione (GSH) pool in the haemolymph. Interestingly, AKH titre was significantly enhanced in haemolymph, while its content in CNS showed non-specific changes in comparable period. Co-injection of AKH with PQ reversed these effects by decreasing protein carbonyl formation, increasing reduced GSH levels, and enhancing the total antioxidant capacity of cell free plasma. Our results indicate that there is a positive feed back regulation between an oxidative stressor action and the level of AKH in insect body, and that AKHs might be involved in the activation of antioxidant protection mechanism. Za použití paraquatu (PQ) byl testován účinek oxidačního stresu na hladinu adipokinetického hormonu (AKH) u ploštice Pyrrhocoris apterus. Oxidační stres vyvolal zvýšení proteinové karbonylace a snížení zásob glutathionu (GSH) v hemolymfě. To bylo spojeno s průkazným zvýšením AKH hladiny v hemolymfě, zatímco obsah AKH v CNS zůstal nezměněn. Injekce směsi AKH a PQ eliminovala tyto změny a zvyšovala oxidační kapacitu hemolymfy. Výsledky naznačují existenci zpětné vazby mezi oxidačním stresem a hladinou AKH a možné zapojení AKH do antioxidační ochrany organismu.
dcterms:title
Zvýšení antioxidační kapacity hemolymfy u Pyrrhocoris apterus indukované adipokinetickým hormonem jako odpověď na oxidační stres Adipokinetic hormone-induced enhancement of antioxidant capacity of Pyrrhocoris apterus hemolymph in response to oxidative stress Adipokinetic hormone-induced enhancement of antioxidant capacity of Pyrrhocoris apterus hemolymph in response to oxidative stress
skos:prefLabel
Adipokinetic hormone-induced enhancement of antioxidant capacity of Pyrrhocoris apterus hemolymph in response to oxidative stress Zvýšení antioxidační kapacity hemolymfy u Pyrrhocoris apterus indukované adipokinetickým hormonem jako odpověď na oxidační stres Adipokinetic hormone-induced enhancement of antioxidant capacity of Pyrrhocoris apterus hemolymph in response to oxidative stress
skos:notation
RIV/60077344:_____/07:00084978!RIV08-AV0-60077344
n3:strany
336;342
n3:aktivita
n6:P n6:V n6:Z
n3:aktivity
P(GA522/07/0788), V, Z(AV0Z50070508)
n3:cisloPeriodika
-
n3:dodaniDat
n13:2008
n3:domaciTvurceVysledku
Alquicer, Glenda n11:3208052 n11:4230930 Krishnan, Natraj
n3:druhVysledku
n18:J
n3:duvernostUdaju
n10:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
408587
n3:idVysledku
RIV/60077344:_____/07:00084978
n3:jazykVysledku
n15:eng
n3:klicovaSlova
adipokinetic hormone; antioxidant activity; oxidative stress
n3:klicoveSlovo
n5:adipokinetic%20hormone n5:oxidative%20stress n5:antioxidant%20activity
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[5655F85F6736]
n3:nazevZdroje
Comparative Biochemistry and Physiology Part C
n3:obor
n14:ED
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:projekt
n12:GA522%2F07%2F0788
n3:rokUplatneniVysledku
n13:2007
n3:svazekPeriodika
146
n3:tvurceVysledku
Alquicer, Glenda Kodrík, Dalibor Večeřa, J. Krishnan, Natraj Socha, Radomír
n3:zamer
n16:AV0Z50070508
s:issn
1532-0456
s:numberOfPages
7