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Statements

Subject Item
n2:RIV%2F60076658%3A12520%2F12%3A43884034%21RIV13-MSM-12520___
rdf:type
n11:Vysledek skos:Concept
dcterms:description
High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion. High performance liquid chromatography (HPLC) in tandem with mass spectrometry (MS) is widely used in chemical and biochemical analysis of the content of measured samples, especially in so-called omics science. Currently, there are methods for processing and analyzing the measured data sets from proteomics as well as metabolomics. However, only some of the problems of processing and analyzing tasks have been compensated for, and even in these cases, they have only been considered independently. Therefore, the current state of data handling is studied. This review describes the currently available methods and techniques commonly used in HPLC-MS for processing and analysis. All the main types of processing and most popular methods are mentioned. However, any overview will fail to be exhaustive. Therefore, some additional literature that goes into further detail is recommended. The review itself reveals some of the important shortcomings of the current state of the art. A list of relevant subtopics relating to different research focuses is provided in the conclusion.
dcterms:title
Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics
skos:prefLabel
Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics Current State of HPLC-MS Data Processing and Analysis in Proteomics and Metabolomics
skos:notation
RIV/60076658:12520/12:43884034!RIV13-MSM-12520___
n11:predkladatel
n12:orjk%3A12520
n3:aktivita
n9:P n9:Z
n3:aktivity
P(ED2.1.00/01.0024), Z(MSM6007665808)
n3:cisloPeriodika
2
n3:dodaniDat
n10:2013
n3:domaciTvurceVysledku
n5:6003524 n5:2963671 n5:4221788
n3:druhVysledku
n4:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
129275
n3:idVysledku
RIV/60076658:12520/12:43884034
n3:jazykVysledku
n21:eng
n3:klicovaSlova
time alignment; mass spectrometry; liquid chromatography; Feature detection
n3:klicoveSlovo
n13:time%20alignment n13:Feature%20detection n13:liquid%20chromatography n13:mass%20spectrometry
n3:kodStatuVydavatele
AE - Stát Spojené arabské emiráty
n3:kontrolniKodProRIV
[2343E46EC5D7]
n3:nazevZdroje
CURRENT PROTEOMICS
n3:obor
n19:CE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n8:ED2.1.00%2F01.0024
n3:rokUplatneniVysledku
n10:2012
n3:svazekPeriodika
9
n3:tvurceVysledku
Štys, Dalibor Vaněk, Jan Urban, Jan
n3:wos
000305654000002
n3:zamer
n20:MSM6007665808
s:issn
1570-1646
s:numberOfPages
14
n17:doi
10.2174/157016412800786248
n6:organizacniJednotka
12520