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Statements

Subject Item
n2:RIV%2F49777513%3A23520%2F12%3A43915509%21RIV13-GA0-23520___
rdf:type
skos:Concept n13:Vysledek
dcterms:description
Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-epsilon-aprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coated with thin layers of HA (200nm and 400 nm). Increasing thickness of HA, however, resulted in a gradual loss of fibrous character. In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased. Clearly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts. The optimal depth of HA was 800 nm. Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-epsilon-aprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coated with thin layers of HA (200nm and 400 nm). Increasing thickness of HA, however, resulted in a gradual loss of fibrous character. In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased. Clearly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts. The optimal depth of HA was 800 nm.
dcterms:title
Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts
skos:prefLabel
Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblasts
skos:notation
RIV/49777513:23520/12:43915509!RIV13-GA0-23520___
n13:predkladatel
n14:orjk%3A23520
n3:aktivita
n11:I n11:S n11:P n11:V n11:Z
n3:aktivity
I, P(2B06130), P(GA202/09/1151), P(GAP304/10/1307), P(GP106/09/P226), P(IAA500390702), P(ME10145), S, V, Z(AV0Z50390512), Z(AV0Z50390703)
n3:cisloPeriodika
ID 428503
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n21:4948289
n3:druhVysledku
n10:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n20:predkladatel
n3:idSjednocenehoVysledku
174354
n3:idVysledku
RIV/49777513:23520/12:43915509
n3:jazykVysledku
n4:eng
n3:klicovaSlova
hydroxyapatit, poly-epsilon-aprolactone/polyvinylalcohol, scaffold, mechanické vlastnosti, mesenchymální kmenové buňky
n3:klicoveSlovo
n16:scaffold n16:poly-epsilon-aprolactone%2Fpolyvinylalcohol n16:mesenchym%C3%A1ln%C3%AD%20kmenov%C3%A9%20bu%C5%88ky n16:mechanick%C3%A9%20vlastnosti n16:hydroxyapatit
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[924EB3DE59E4]
n3:nazevZdroje
Journal of Biomedicine and Biotechnology
n3:obor
n15:JJ
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
10
n3:projekt
n6:ME10145 n6:IAA500390702 n6:2B06130 n6:GA202%2F09%2F1151 n6:GAP304%2F10%2F1307 n6:GP106%2F09%2FP226
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
2012
n3:tvurceVysledku
Rampichová, Michala Kocourek, Tomáš Vysloužilová, Lucie Buzgo, Matej Lukáš, David Tvrdík, Daniel Jelínek, Miroslav Prosecká, Eva Amler, Evžen Kochová, Petra
n3:wos
000301378600001
n3:zamer
n19:AV0Z50390703 n19:AV0Z50390512
s:issn
1110-7243
s:numberOfPages
10
n9:doi
10.1155/2012/428503
n5:organizacniJednotka
23520