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Statements

Subject Item
n2:RIV%2F46747885%3A24410%2F10%3A%230000768%21RIV11-GA0-24410___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Non-woven textile mesh from polyglycolic acid (PGA) was found as a proper material for chondrocyte adhesion but worse for their proliferation. Neither hyaluronic acid nor chitosan nor polyvinyl alcohol (PVA) increased chondrocyte adhesion. However, chondrocyte proliferation suffered from acidic byproducts of PGA degradation. However, the addition of PVA and/or chitosan into a wet-laid non-woven textile mesh from PGA improved chondrocyte proliferation seeded in vitro on the PGA-based composite scaffold namely due to a diminished acidification of their microenvironment. This PVA/PGA composite mesh used in combination with a proper hydrogel minimized the negative effect of PGA degradation without dropping positive parameters of the PGA wet-laid non-woven textile mesh. Non-woven textile mesh from polyglycolic acid (PGA) was found as a proper material for chondrocyte adhesion but worse for their proliferation. Neither hyaluronic acid nor chitosan nor polyvinyl alcohol (PVA) increased chondrocyte adhesion. However, chondrocyte proliferation suffered from acidic byproducts of PGA degradation. However, the addition of PVA and/or chitosan into a wet-laid non-woven textile mesh from PGA improved chondrocyte proliferation seeded in vitro on the PGA-based composite scaffold namely due to a diminished acidification of their microenvironment. This PVA/PGA composite mesh used in combination with a proper hydrogel minimized the negative effect of PGA degradation without dropping positive parameters of the PGA wet-laid non-woven textile mesh.
dcterms:title
Non-Woven PGA/PVA Fibrous Mesh as an Appropriate Scaffold for Chondrocyte Proliferation Non-Woven PGA/PVA Fibrous Mesh as an Appropriate Scaffold for Chondrocyte Proliferation
skos:prefLabel
Non-Woven PGA/PVA Fibrous Mesh as an Appropriate Scaffold for Chondrocyte Proliferation Non-Woven PGA/PVA Fibrous Mesh as an Appropriate Scaffold for Chondrocyte Proliferation
skos:notation
RIV/46747885:24410/10:#0000768!RIV11-GA0-24410___
n3:aktivita
n18:Z n18:S n18:P
n3:aktivity
P(1M0510), P(2B06130), P(GA202/09/1151), P(GAP304/10/1307), P(IAA500390702), S, Z(AV0Z50390512), Z(AV0Z50390703)
n3:cisloPeriodika
5
n3:dodaniDat
n14:2011
n3:domaciTvurceVysledku
n10:3868427 n10:8327602 n10:5094968
n3:druhVysledku
n19:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
275102
n3:idVysledku
RIV/46747885:24410/10:#0000768
n3:jazykVysledku
n4:eng
n3:klicovaSlova
PGA; PVA; Non-woven Textile; Chondrocyte; Tissue Engineering
n3:klicoveSlovo
n9:Tissue%20Engineering n9:PVA n9:PGA n9:Chondrocyte n9:Non-woven%20Textile
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[B0784B486B5D]
n3:nazevZdroje
PHYSIOLOGICAL RESEARCH
n3:obor
n17:FP
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
9
n3:projekt
n7:IAA500390702 n7:1M0510 n7:GA202%2F09%2F1151 n7:2B06130 n7:GAP304%2F10%2F1307
n3:rokUplatneniVysledku
n14:2010
n3:svazekPeriodika
59
n3:tvurceVysledku
Filová, Eva Košťáková, Eva Prosecká, Eva Plencner, Martin Amler, Evžen Lytvynets, Andriy Rampichová, Michala Lukáš, David Ocheretna, Larysa
n3:wos
000284489300017
n3:zamer
n5:AV0Z50390703 n5:AV0Z50390512
s:issn
0862-8408
s:numberOfPages
9
n12:organizacniJednotka
24410