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Statements

Subject Item
n2:RIV%2F46747885%3A24210%2F14%3A%230006542%21RIV15-MSM-24210___
rdf:type
skos:Concept n13:Vysledek
rdfs:seeAlso
http://www.scopus.com/authid/detail.url?authorId=54950669200
dcterms:description
This article describes the design of equipment for the production of small-diameter fiber tubular bodies, which can be used as carrier of tissue cells, so called scaffold. It is also described the production and creation of a simulation model describing the behaviour of the tubular body under internal pressure. For this purpose electrospinning device has been created which allows obtaining the parallel fiber orientation, which is required for effective penetration of cell and mechanical properties of artifical flood vessel. Prepared scaffolds were subjected to mechanical tsting for a determination of a suitable material model.Subsequently, the FEM model of the scaffold loaded with an internal overpressure, which corresponds to normal blood pressure (120/80 mmHg) was established. The results allow assessing the behaviour of the scaffold during cell cultivation and their subsequent proliferation in fibrous structure, because a stimulation of cell proliferation is achieved by a flowing of a nutrient solution in the scaffold under changeable pressure. Based on obtained results an optimization of scaffolds was recommended. This article describes the design of equipment for the production of small-diameter fiber tubular bodies, which can be used as carrier of tissue cells, so called scaffold. It is also described the production and creation of a simulation model describing the behaviour of the tubular body under internal pressure. For this purpose electrospinning device has been created which allows obtaining the parallel fiber orientation, which is required for effective penetration of cell and mechanical properties of artifical flood vessel. Prepared scaffolds were subjected to mechanical tsting for a determination of a suitable material model.Subsequently, the FEM model of the scaffold loaded with an internal overpressure, which corresponds to normal blood pressure (120/80 mmHg) was established. The results allow assessing the behaviour of the scaffold during cell cultivation and their subsequent proliferation in fibrous structure, because a stimulation of cell proliferation is achieved by a flowing of a nutrient solution in the scaffold under changeable pressure. Based on obtained results an optimization of scaffolds was recommended.
dcterms:title
Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel
skos:prefLabel
Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel Experimental and Numerical Study of Mechanical Properties of Artificial Blood Vessel
skos:notation
RIV/46747885:24210/14:#0006542!RIV15-MSM-24210___
n3:aktivita
n4:I n4:P
n3:aktivity
I, P(EE2.3.30.0024), P(EE2.3.30.0065), P(LO1201)
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n15:4384032
n3:druhVysledku
n12:D
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
15789
n3:idVysledku
RIV/46747885:24210/14:#0006542
n3:jazykVysledku
n14:eng
n3:klicovaSlova
Artificial blood vessel; Electrospinning; FEM model
n3:klicoveSlovo
n8:Electrospinning n8:FEM%20model n8:Artificial%20blood%20vessel
n3:kontrolniKodProRIV
[233CB0E18B12]
n3:mistoKonaniAkce
Mariánské Lázně
n3:mistoVydani
Plzeň
n3:nazevZdroje
Experimental Stress Analysis 2014
n3:obor
n19:JQ
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:projekt
n9:LO1201 n9:EE2.3.30.0065 n9:EE2.3.30.0024
n3:rokUplatneniVysledku
n7:2014
n3:tvurceVysledku
Lepšík, Petr Novák, Ondřej Vosáhlo, Josef Petrů, Michal
n3:typAkce
n17:EUR
n3:zahajeniAkce
2014-01-01+01:00
s:numberOfPages
2
n16:hasPublisher
Výzkumný a zkušební ústav Plzeň s.r.o.
n18:isbn
978-80-231-0377-6
n22:organizacniJednotka
24210