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Statements

Subject Item
n2:RIV%2F28778758%3A_____%2F12%3A%230000023%21RIV13-TA0-28778758
rdf:type
n11:Vysledek skos:Concept
dcterms:description
The aim of this study is to demonstrate antimicrobial activity of selected positively charged water-soluble phthalocyanines. 12 phthalocyanine derivatives were used for this study. All the tested compounds were synthesized in Centre of Organic Chemistry (COC, Rybitví, Czech republic). Water soluble phthalocyanine derivatives were prepared by peripherally substitution of the phthalocyanine skeleton with the aim to prepare cationic phthalocyanines with an ability to have a wide-spectrum antimicrobial effect. To determine the antimicrobial effects of phthalocyanines, bacterial strains Escherichia coli CCM 3988, Enterococcus faecalis CCM 4224, and Pseudomonas aeruginosa CCM 1960 were used. Phthalocyanine samples were tested in two concentrations - 0.1 and 0.5 g/l. In a sterile vial, phthalocyanine solution with the bacteria was shaken under artificial light at room temperature. The suspension was sampled at 1st, 2nd and 3rd hour. Samples were subsequently inoculated on Petri dishes with nutrient medium. The control sample was prepared by the same procedure. After the cultivation of Petri dishes, accrued colonies were counted and the results were expressed in CFU/ml. Antimicrobial action of phthalocyanines has been demonstrated. The aim of this study is to demonstrate antimicrobial activity of selected positively charged water-soluble phthalocyanines. 12 phthalocyanine derivatives were used for this study. All the tested compounds were synthesized in Centre of Organic Chemistry (COC, Rybitví, Czech republic). Water soluble phthalocyanine derivatives were prepared by peripherally substitution of the phthalocyanine skeleton with the aim to prepare cationic phthalocyanines with an ability to have a wide-spectrum antimicrobial effect. To determine the antimicrobial effects of phthalocyanines, bacterial strains Escherichia coli CCM 3988, Enterococcus faecalis CCM 4224, and Pseudomonas aeruginosa CCM 1960 were used. Phthalocyanine samples were tested in two concentrations - 0.1 and 0.5 g/l. In a sterile vial, phthalocyanine solution with the bacteria was shaken under artificial light at room temperature. The suspension was sampled at 1st, 2nd and 3rd hour. Samples were subsequently inoculated on Petri dishes with nutrient medium. The control sample was prepared by the same procedure. After the cultivation of Petri dishes, accrued colonies were counted and the results were expressed in CFU/ml. Antimicrobial action of phthalocyanines has been demonstrated.
dcterms:title
Test of phthalocyanine antimicrobial activity Test of phthalocyanine antimicrobial activity
skos:prefLabel
Test of phthalocyanine antimicrobial activity Test of phthalocyanine antimicrobial activity
skos:notation
RIV/28778758:_____/12:#0000023!RIV13-TA0-28778758
n11:predkladatel
n15:ico%3A28778758
n3:aktivita
n10:P
n3:aktivity
P(TA01010356)
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n12:5652146 n12:4385691
n3:druhVysledku
n17:D
n3:duvernostUdaju
n21:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
173986
n3:idVysledku
RIV/28778758:_____/12:#0000023
n3:jazykVysledku
n14:eng
n3:klicovaSlova
microorganisms; antimicrobial activity; phthalocyanines
n3:klicoveSlovo
n19:microorganisms n19:phthalocyanines n19:antimicrobial%20activity
n3:kontrolniKodProRIV
[C4C531DB6F3D]
n3:mistoKonaniAkce
Brno
n3:mistoVydani
Ostrava
n3:nazevZdroje
Conference Proceedings Nanocon 2012
n3:obor
n8:EE
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
7
n3:projekt
n6:TA01010356
n3:rokUplatneniVysledku
n7:2012
n3:tvurceVysledku
Hrdinová, Zuzana Lev, Jaroslav Konečná, Marie Kalhotka, Libor Kořínková, Radka Přichystalová, Jitka Kubáč, Lubomír
n3:typAkce
n4:WRD
n3:zahajeniAkce
2012-10-23+02:00
s:numberOfPages
6
n18:hasPublisher
Tanger s.r.o.
n16:isbn
978-80-87294-32-1