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Statements

Subject Item
n2:RIV%2F25281844%3A_____%2F10%3A%230000017%21RIV13-MPO-25281844
rdf:type
n11:Vysledek skos:Concept
rdfs:seeAlso
http://www.nanocon.eu/files/proceedings/nanocon_10/lists/papers/430.pdf
dcterms:description
Hyaluronan is a high molecular weight unbranched glycosaminoglycan, composed of repeating disaccharides. Hyaluronan is naturally found in many tissues of the body, such as skin, cartilage, and the vitreous humour. It is therefore well suited to biomedical applications targeting these tissues. The preparation of hyaluronan nanofibres is based on electrospinning method of hyaluronan solutions with the appropriate physical properties. Because the viscosity is known as one of the most important parameter that influences the nanofibres formation, the effect of molecular weight, concentration of HA and used´solvent on apparent viscosity was studied. Also other solutions properties, such a surface tension and conductivity were measured. Prepared solutions were electrospinned and formation of nanofibres was observed. The best parameters of hyaluronan solutions were chosen. The hyaluronan nanofibres were prepared. Also the critical overlap concentration (c*) was determined for water solutions of hyaluronan. Above this concentration the influence of overlapping molecular domains becomes significant. Hyaluronan is a high molecular weight unbranched glycosaminoglycan, composed of repeating disaccharides. Hyaluronan is naturally found in many tissues of the body, such as skin, cartilage, and the vitreous humour. It is therefore well suited to biomedical applications targeting these tissues. The preparation of hyaluronan nanofibres is based on electrospinning method of hyaluronan solutions with the appropriate physical properties. Because the viscosity is known as one of the most important parameter that influences the nanofibres formation, the effect of molecular weight, concentration of HA and used´solvent on apparent viscosity was studied. Also other solutions properties, such a surface tension and conductivity were measured. Prepared solutions were electrospinned and formation of nanofibres was observed. The best parameters of hyaluronan solutions were chosen. The hyaluronan nanofibres were prepared. Also the critical overlap concentration (c*) was determined for water solutions of hyaluronan. Above this concentration the influence of overlapping molecular domains becomes significant.
dcterms:title
Physical properties of native hyaluronan solutions for preparation of nanofibres Physical properties of native hyaluronan solutions for preparation of nanofibres
skos:prefLabel
Physical properties of native hyaluronan solutions for preparation of nanofibres Physical properties of native hyaluronan solutions for preparation of nanofibres
skos:notation
RIV/25281844:_____/10:#0000017!RIV13-MPO-25281844
n3:aktivita
n18:P
n3:aktivity
P(FR-TI1/151)
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n5:2193035 n5:3194744 n5:4042905
n3:druhVysledku
n13:D
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
278920
n3:idVysledku
RIV/25281844:_____/10:#0000017
n3:jazykVysledku
n14:eng
n3:klicovaSlova
hyaluronan; nanofibres; viscosity
n3:klicoveSlovo
n7:viscosity n7:nanofibres n7:hyaluronan
n3:kontrolniKodProRIV
[26402C41D9E3]
n3:mistoKonaniAkce
Olomouc
n3:mistoVydani
Olomouc
n3:nazevZdroje
Nanocon 2010
n3:obor
n6:EI
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n16:FR-TI1%2F151
n3:rokUplatneniVysledku
n8:2010
n3:tvurceVysledku
Bilerová, Helena Hánošová, Veronika Velebný, Vladimír
n3:typAkce
n12:WRD
n3:zahajeniAkce
2010-10-12+02:00
s:numberOfPages
1
n17:hasPublisher
Tanger spol. s.r.o.
n21:isbn
978-80-87294-18-5