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Statements

Subject Item
n2:RIV%2F00843989%3A_____%2F11%3A00102141%21RIV12-MZ0-00843989
rdf:type
skos:Concept n7:Vysledek
dcterms:description
During the pandemy caused by novel influenza A virus (subgroup H1N1), a significant number of patients became critically ill from respiratory failure. In the most severe cases of primary pneumonia, patients develop refractory hypoxemic acute respiratory distress syndrome (ARDS) with typical computed tomographic findings of multi-lobar alveolar opacities and extremely reduced pulmonary airspace. To reduce the risk of injurious ventilation and promote survival, some authors recommend the use of extracorporeal membrane oxygenation (ECMO). Unfortunately, ECMO is expensive, associated with serious complications, and available at very few centers. Other therapeutic options are clearly needed. Here we report three patients with severe influenza pneumonia who recovered following treatment with porcine surfactant (Tab. 1, Fig. 3, Ref. 6). During the pandemy caused by novel influenza A virus (subgroup H1N1), a significant number of patients became critically ill from respiratory failure. In the most severe cases of primary pneumonia, patients develop refractory hypoxemic acute respiratory distress syndrome (ARDS) with typical computed tomographic findings of multi-lobar alveolar opacities and extremely reduced pulmonary airspace. To reduce the risk of injurious ventilation and promote survival, some authors recommend the use of extracorporeal membrane oxygenation (ECMO). Unfortunately, ECMO is expensive, associated with serious complications, and available at very few centers. Other therapeutic options are clearly needed. Here we report three patients with severe influenza pneumonia who recovered following treatment with porcine surfactant (Tab. 1, Fig. 3, Ref. 6).
dcterms:title
Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1) Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1)
skos:prefLabel
Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1) Exogenous surfactant as a component of complex non-ECMO therapy of ARDS caused by influenza A virus (2009 H1N1)
skos:notation
RIV/00843989:_____/11:00102141!RIV12-MZ0-00843989
n7:predkladatel
n8:ico%3A00843989
n3:aktivita
n6:V
n3:aktivity
V
n3:cisloPeriodika
4
n3:dodaniDat
n10:2012
n3:domaciTvurceVysledku
n4:6490867 n4:7289626 n4:7788363 n4:8103879 n4:7060629 n4:7477457 n4:4207645 n4:4704096 n4:8047324
n3:druhVysledku
n16:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
198662
n3:idVysledku
RIV/00843989:_____/11:00102141
n3:jazykVysledku
n11:eng
n3:klicovaSlova
H1N1; influenza A; ARDS; surfactant
n3:klicoveSlovo
n12:surfactant n12:influenza%20A n12:ARDS n12:H1N1
n3:kodStatuVydavatele
SK - Slovenská republika
n3:kontrolniKodProRIV
[D9F52B79A07A]
n3:nazevZdroje
Bratislavské lekárske listy
n3:obor
n15:FN
n3:pocetDomacichTvurcuVysledku
9
n3:pocetTvurcuVysledku
9
n3:rokUplatneniVysledku
n10:2011
n3:svazekPeriodika
112
n3:tvurceVysledku
Sklienka, Peter Tichý, Jiří Máca, Jan Sukeník, Pavol Szturz, Pavel Chýlek, Václav Czerný, Daniel Jahoda, Jan Kula, Roman
n3:wos
000289503300014
s:issn
0006-9248
s:numberOfPages
5