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Statements

Subject Item
n2:RIV%2F00843989%3A_____%2F11%3A00102073%21RIV12-MZ0-00843989
rdf:type
skos:Concept n12:Vysledek
dcterms:description
Aim. Acute interstitial pneumonia is characterized by rapid progressive dyspnoea degenerating into respiratory failure requiring mechanical ventilation. Acute interstitial pneumonia (AIP) and idiopathic pulmonary fibrosis (IPF) are separate clinic/pathological entities although overlap may be present. It is well-known that patients with IPF have increased risk of lung carcinoma; Adenocarcinoma in connection with IPF is less common. Moreover the subtype of adenocarcinoma, diffuse bronchoalveolar carcinoma has not yet been described. Case report. We report the case of 45 yr old former hockey player with increased bilateral reticular shadowing on chest radiograph, dyspnoea, velcro-like crackles, restrictive respiratory disease and mixed high-resolution computed tomography finding. During brief in-patient treatment the patient developed acute respiratory failure accompanied by multiorgan failure and disseminated coagulopathy. Deterioration of the microcirculation was followed by loss of peripheral vascular resistance, which was irreversible even with normalization of the blood gases achieved by extracorporeal membrane oxygenation. At autopsy, bronchoalveolar carcinoma in usual interstitial pneumonia (UIP) combined with areas of alveolar damage with hyaline membranes was found. Conclusion. This case alerts clinicians to unusual idiopathic pulmonary fibrosis manifestations and its complications. Close collaboration between clinicians, pathologists and laboratory physicians is highly recommended for early diagnosis and appropriate treatment. Aim. Acute interstitial pneumonia is characterized by rapid progressive dyspnoea degenerating into respiratory failure requiring mechanical ventilation. Acute interstitial pneumonia (AIP) and idiopathic pulmonary fibrosis (IPF) are separate clinic/pathological entities although overlap may be present. It is well-known that patients with IPF have increased risk of lung carcinoma; Adenocarcinoma in connection with IPF is less common. Moreover the subtype of adenocarcinoma, diffuse bronchoalveolar carcinoma has not yet been described. Case report. We report the case of 45 yr old former hockey player with increased bilateral reticular shadowing on chest radiograph, dyspnoea, velcro-like crackles, restrictive respiratory disease and mixed high-resolution computed tomography finding. During brief in-patient treatment the patient developed acute respiratory failure accompanied by multiorgan failure and disseminated coagulopathy. Deterioration of the microcirculation was followed by loss of peripheral vascular resistance, which was irreversible even with normalization of the blood gases achieved by extracorporeal membrane oxygenation. At autopsy, bronchoalveolar carcinoma in usual interstitial pneumonia (UIP) combined with areas of alveolar damage with hyaline membranes was found. Conclusion. This case alerts clinicians to unusual idiopathic pulmonary fibrosis manifestations and its complications. Close collaboration between clinicians, pathologists and laboratory physicians is highly recommended for early diagnosis and appropriate treatment.
dcterms:title
Acute interstitial pneumonia (Hamman-Rich syndrome) in idiopathic pulmonary fibrosis and bronchoalveolar carcinoma: a case report Acute interstitial pneumonia (Hamman-Rich syndrome) in idiopathic pulmonary fibrosis and bronchoalveolar carcinoma: a case report
skos:prefLabel
Acute interstitial pneumonia (Hamman-Rich syndrome) in idiopathic pulmonary fibrosis and bronchoalveolar carcinoma: a case report Acute interstitial pneumonia (Hamman-Rich syndrome) in idiopathic pulmonary fibrosis and bronchoalveolar carcinoma: a case report
skos:notation
RIV/00843989:_____/11:00102073!RIV12-MZ0-00843989
n12:predkladatel
n13:ico%3A00843989
n3:aktivita
n10:V
n3:aktivity
V
n3:cisloPeriodika
4
n3:dodaniDat
n8:2012
n3:domaciTvurceVysledku
n4:7095066 n4:4880323 n4:6311008 n4:3867781 n4:9856668 n4:6289754 n4:7289626 n4:2070413
n3:druhVysledku
n17:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
184537
n3:idVysledku
RIV/00843989:_____/11:00102073
n3:jazykVysledku
n15:eng
n3:klicovaSlova
acute respiratory failure; interstitial lung disease; adenocarcinoma
n3:klicoveSlovo
n16:adenocarcinoma n16:interstitial%20lung%20disease n16:acute%20respiratory%20failure
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[BC47986F3115]
n3:nazevZdroje
Biomedical papers
n3:obor
n18:FA
n3:pocetDomacichTvurcuVysledku
8
n3:pocetTvurcuVysledku
8
n3:rokUplatneniVysledku
n8:2011
n3:svazekPeriodika
155
n3:tvurceVysledku
Hrabovský, Vladimír Plášek, Jiří Dvořáčková, Jana Mokošová, Radka Daněk, Tomáš Martínek, Arnošt Jahoda, Jan Trulíková, Kristína
n3:wos
000299697000015
s:issn
1213-8118
s:numberOfPages
6
n14:doi
10.5507/bp.2011.039