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Statements

Subject Item
n2:RIV%2F00843989%3A_____%2F10%3A00101244%21RIV11-MZ0-00843989
rdf:type
skos:Concept n17:Vysledek
dcterms:description
A 30-year old female with persisting paresthesia of acral forelimbs, right hand weakness and double vision underwent brain angiography. This revealed both internal carotid artery stenoses and stenoses of the anterior cerebral arteries. After contrast medium application characteristic moyamoya markers (coiled and elongated vessels with „smoke puffs carried away by breeze) were found. The histological findings included obstruction of vessel lumen, fibrocellular intimal thickening, tortuosity and disruption of internal elastic lamina and, attenuation of media together with decreased SMA positivity. We confirmed a defect of the internal elastic membrane of the muscular arteria using elastica and alcian blue (Müller) stains and progressive intimal thickening accompanied by findings of abnormal smooth muscle cells and, VEGF and VEGFR expression in intima. Nestin positivity in endothelium of arteria showed that endothelial cells were activa A 30-year old female with persisting paresthesia of acral forelimbs, right hand weakness and double vision underwent brain angiography. This revealed both internal carotid artery stenoses and stenoses of the anterior cerebral arteries. After contrast medium application characteristic moyamoya markers (coiled and elongated vessels with „smoke puffs carried away by breeze) were found. The histological findings included obstruction of vessel lumen, fibrocellular intimal thickening, tortuosity and disruption of internal elastic lamina and, attenuation of media together with decreased SMA positivity. We confirmed a defect of the internal elastic membrane of the muscular arteria using elastica and alcian blue (Müller) stains and progressive intimal thickening accompanied by findings of abnormal smooth muscle cells and, VEGF and VEGFR expression in intima. Nestin positivity in endothelium of arteria showed that endothelial cells were activa
dcterms:title
Moyamoya disease is associated with endothelial activity detected by anti-nestin antibody Moyamoya disease is associated with endothelial activity detected by anti-nestin antibody
skos:prefLabel
Moyamoya disease is associated with endothelial activity detected by anti-nestin antibody Moyamoya disease is associated with endothelial activity detected by anti-nestin antibody
skos:notation
RIV/00843989:_____/10:00101244!RIV11-MZ0-00843989
n4:aktivita
n15:V n15:Z
n4:aktivity
V, Z(MSM6198959216)
n4:cisloPeriodika
2
n4:dodaniDat
n5:2011
n4:domaciTvurceVysledku
n6:8937222 n6:6619746 n6:4867459 n6:7095066 n6:1302914 n6:7325746 n6:4088166
n4:druhVysledku
n7:J
n4:duvernostUdaju
n10:S
n4:entitaPredkladatele
n14:predkladatel
n4:idSjednocenehoVysledku
272733
n4:idVysledku
RIV/00843989:_____/10:00101244
n4:jazykVysledku
n16:eng
n4:klicovaSlova
Moyamoya disease; Nestin; VEGF(R); endothelial activation
n4:klicoveSlovo
n8:Nestin n8:VEGF%28R%29 n8:Moyamoya%20disease n8:endothelial%20activation
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[34A33954E5B6]
n4:nazevZdroje
Biomedical papers
n4:obor
n9:FP
n4:pocetDomacichTvurcuVysledku
7
n4:pocetTvurcuVysledku
8
n4:rokUplatneniVysledku
n5:2010
n4:svazekPeriodika
154
n4:tvurceVysledku
Procházka, Václav Chmelová, Jana Kraft, Otakar Kolář, Z. Dvořáčková, Jana Hrbáč, Tomáš Širůček, Pavel Čuřík, Romuald
n4:wos
000279802800008
n4:zamer
n11:MSM6198959216
s:issn
1213-8118
s:numberOfPages
4