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Statements

Subject Item
n2:RIV%2F00669806%3A_____%2F11%3A10107683%21RIV12-MZ0-00669806
rdf:type
skos:Concept n11:Vysledek
rdfs:seeAlso
http://www.ncbi.nlm.nih.gov/pubmed/21699377
dcterms:description
The retrospective study evaluated the secondary clinical risk score at relapse, the prognostic significance of pre-transplant positron emission tomography (PET), and complete remission (CR) assessed by computed tomography (CT) after salvage chemotherapy before autologous stem cell transplant (ASCT) in 76 patients with relapsed/refractory Hodgkin lymphoma (HL). Median follow-up after ASCT was 23 months. Overall 11/20 PET-positive and 14/56 PET-negative patients relapsed after ASCT. In univariate analysis, only PET negativity before ASCT was significantly associated with better 2-year progression-free survival (PFS) and 2-year overall survival (OS). Other factors were not significant. In multivariate analysis, none of the evaluated factors were significant for PFS and OS. However, positive pre-transplant PET identified a population with worse PFS and OS at least in univariate analysis. The retrospective study evaluated the secondary clinical risk score at relapse, the prognostic significance of pre-transplant positron emission tomography (PET), and complete remission (CR) assessed by computed tomography (CT) after salvage chemotherapy before autologous stem cell transplant (ASCT) in 76 patients with relapsed/refractory Hodgkin lymphoma (HL). Median follow-up after ASCT was 23 months. Overall 11/20 PET-positive and 14/56 PET-negative patients relapsed after ASCT. In univariate analysis, only PET negativity before ASCT was significantly associated with better 2-year progression-free survival (PFS) and 2-year overall survival (OS). Other factors were not significant. In multivariate analysis, none of the evaluated factors were significant for PFS and OS. However, positive pre-transplant PET identified a population with worse PFS and OS at least in univariate analysis.
dcterms:title
Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma
skos:prefLabel
Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma Pre-transplant positron emission tomography in patients with relapsed Hodgkin lymphoma
skos:notation
RIV/00669806:_____/11:10107683!RIV12-MZ0-00669806
n11:predkladatel
n12:ico%3A00669806
n3:aktivita
n10:V n10:Z n10:S n10:I n10:N
n3:aktivity
I, N, S, V, Z(MSM0021620808)
n3:cisloPeriodika
9
n3:dodaniDat
n6:2012
n3:domaciTvurceVysledku
n8:6662986
n3:druhVysledku
n19:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
223186
n3:idVysledku
RIV/00669806:_____/11:10107683
n3:jazykVysledku
n16:eng
n3:klicovaSlova
analogous stem cell transplant; PET; Hodgkin lymphoma
n3:klicoveSlovo
n5:PET n5:analogous%20stem%20cell%20transplant n5:Hodgkin%20lymphoma
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[BDABF57FCD69]
n3:nazevZdroje
Leukemia and Lymphoma
n3:obor
n18:FD
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
12
n3:rokUplatneniVysledku
n6:2011
n3:svazekPeriodika
52
n3:tvurceVysledku
Trněný, Marek Pytlík, Robert Mayer, Jiří Marková, Jana Koza, Vladimír Kozák, Tomáš Belada, David Steinerová, Kateřina Trnková, Marie Mociková, Heidi Král, Zdeněk Žák, Pavel
n3:wos
000294228100010
n3:zamer
n13:MSM0021620808
s:issn
1042-8194
s:numberOfPages
7
n17:doi
10.3109/10428194.2011.573889