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Statements

Subject Item
n2:RIV%2F00216305%3A26620%2F14%3APU112619%21RIV15-MSM-26620___
rdf:type
n10:Vysledek skos:Concept
dcterms:description
Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT)is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinityof this protein to any reactive species including metals and reactive oxygen species. The purpose ofthis study was to determine the metallothionein–quantum dots interactions that were investigated byspectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results weresupported by statistical analysis and considered as significant. Further, these interactions were analysedusing gel electrophoresis, where MT aggregates forming after interactions with QDs were detected. Usingdifferential pulse voltammetry Brdicka reaction, QDs and MT were studied. This method allowed us toconfirm spectral results and, moreover, to observe the changes in MT structure causing new voltammetric Nanoparticles have gained increasing interest in medical and in vivo applications. Metallothionein (MT)is well known as a maintainer of metal ions balance in intracellular space. This is due to high affinityof this protein to any reactive species including metals and reactive oxygen species. The purpose ofthis study was to determine the metallothionein–quantum dots interactions that were investigated byspectral and electrochemical techniques. CuS, CdS, PbS, and CdTe quantum dots (QDs) were analysed.The highest intensity was shown for CdTe, than for CdS measured by fluorescence. These results weresupported by statistical analysis and considered as significant. Further, these interactions were analysedusing gel electrophoresis, where MT aggregates forming after interactions with QDs were detected. Usingdifferential pulse voltammetry Brdicka reaction, QDs and MT were studied. This method allowed us toconfirm spectral results and, moreover, to observe the changes in MT structure causing new voltammetric
dcterms:title
Study of metallothionein–quantum dots interactions Study of metallothionein–quantum dots interactions
skos:prefLabel
Study of metallothionein–quantum dots interactions Study of metallothionein–quantum dots interactions
skos:notation
RIV/00216305:26620/14:PU112619!RIV15-MSM-26620___
n4:aktivita
n16:O n16:P
n4:aktivity
O, P(ED1.1.00/02.0068)
n4:cisloPeriodika
1
n4:dodaniDat
n7:2015
n4:domaciTvurceVysledku
n8:4995775 n8:6044786 n8:2104237 n8:8541698 n8:6359914 n8:3790185 n8:2307049
n4:druhVysledku
n14:J
n4:duvernostUdaju
n18:S
n4:entitaPredkladatele
n17:predkladatel
n4:idSjednocenehoVysledku
48299
n4:idVysledku
RIV/00216305:26620/14:PU112619
n4:jazykVysledku
n13:eng
n4:klicovaSlova
Electrochemical detection, Metallothionein, Quantum dots, Interaction
n4:klicoveSlovo
n5:Metallothionein n5:Interaction n5:Quantum%20dots n5:Electrochemical%20detection
n4:kodStatuVydavatele
NL - Nizozemsko
n4:kontrolniKodProRIV
[ABD2D2D68522]
n4:nazevZdroje
Colloids and Surfaces B: Biointerfaces
n4:obor
n15:BO
n4:pocetDomacichTvurcuVysledku
7
n4:pocetTvurcuVysledku
7
n4:projekt
n9:ED1.1.00%2F02.0068
n4:rokUplatneniVysledku
n7:2014
n4:svazekPeriodika
117
n4:tvurceVysledku
Tmejová, Kateřina Kizek, René Adam, Vojtěch Křížková, Soňa Kopel, Pavel Trnková, Libuše Hynek, David
n4:wos
000336018700070
s:issn
0927-7765
s:numberOfPages
4
n11:organizacniJednotka
26620