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Statements

Subject Item
n2:RIV%2F00216305%3A26620%2F14%3APU111699%21RIV15-MSM-26620___
rdf:type
skos:Concept n13:Vysledek
dcterms:description
Recent developments in mass spectrometry have introduced clinical proteomics to the forefront of diseases diagnosis, offering reliable, robust and efficient analytical method for biomarker discovery and monitoring. MALDI-TOF is a powerful tool for surveying proteins and peptides comprising the realm for clinical analysis. MALDI-TOF has the potential to revolutionize cancer diagnostics by facilitating biomarker discovery, enabling tissue imaging and quantifying biomarker levels. Healthy (control) and cancerous tissues can be analyzed on the basis of mass spectrometry (MALDI-TOF) imaging to identify cancer-specific changes that may prove to be clinically useful. We review MALDI-TOF profiling techniques as tools for detection of cancer biomarkers in various cancers. We mainly discuss recent advances including period from 2011 to 2013 Recent developments in mass spectrometry have introduced clinical proteomics to the forefront of diseases diagnosis, offering reliable, robust and efficient analytical method for biomarker discovery and monitoring. MALDI-TOF is a powerful tool for surveying proteins and peptides comprising the realm for clinical analysis. MALDI-TOF has the potential to revolutionize cancer diagnostics by facilitating biomarker discovery, enabling tissue imaging and quantifying biomarker levels. Healthy (control) and cancerous tissues can be analyzed on the basis of mass spectrometry (MALDI-TOF) imaging to identify cancer-specific changes that may prove to be clinically useful. We review MALDI-TOF profiling techniques as tools for detection of cancer biomarkers in various cancers. We mainly discuss recent advances including period from 2011 to 2013
dcterms:title
MALDI-TOF MS as evolving cancer diagnostic tool: A review MALDI-TOF MS as evolving cancer diagnostic tool: A review
skos:prefLabel
MALDI-TOF MS as evolving cancer diagnostic tool: A review MALDI-TOF MS as evolving cancer diagnostic tool: A review
skos:notation
RIV/00216305:26620/14:PU111699!RIV15-MSM-26620___
n3:aktivita
n18:S n18:P
n3:aktivity
P(ED1.1.00/02.0068), S
n3:cisloPeriodika
1
n3:dodaniDat
n4:2015
n3:domaciTvurceVysledku
n7:2104237 Merlos Rodrigo, Miguel Ángel n7:8740658 n7:2307049 Moulick, Amitava n7:4995775
n3:druhVysledku
n6:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
27015
n3:idVysledku
RIV/00216305:26620/14:PU111699
n3:jazykVysledku
n15:eng
n3:klicovaSlova
Mass spectrometry, Imaging, Tissue profiling, Cancer biomarkers, MALDI-TOF
n3:klicoveSlovo
n11:Tissue%20profiling n11:MALDI-TOF n11:Imaging n11:Mass%20spectrometry n11:Cancer%20biomarkers
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[44948BAEF868]
n3:nazevZdroje
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
n3:obor
n5:CG
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n16:ED1.1.00%2F02.0068
n3:rokUplatneniVysledku
n4:2014
n3:svazekPeriodika
95
n3:tvurceVysledku
Moulick, Amitava Zítka, Ondřej Adam, Vojtěch Křížková, Soňa Merlos Rodrigo, Miguel Ángel Kizek, René
s:issn
0731-7085
s:numberOfPages
11
n14:organizacniJednotka
26620