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Statements

Subject Item
n2:RIV%2F00216305%3A26620%2F14%3APU111696%21RIV15-MSM-26620___
rdf:type
n10:Vysledek skos:Concept
dcterms:description
The aim of this study was to investigate the interaction between lead ions and ethylenediaminetetraacetic acid (EDTA) in plasma. EDTA is widely used in medicine as anticoagulant agent. Understanding of the influence of EDTA on the electrochemical lead ions determination is very suitable for the determination of lead ions at patients with increased metals levels in body fluids. Further, the changes of metal ions levels (Zn, Cd, Pb and Cu) were monitored in the blood plasma of child patients treated for various oncological diseases. Electrochemical method differential pulse voltammetry with fully automated system and atomic absorption spectrometry was used for determination of the metal ions. It was found an increased amount of metal ions in the blood plasma of patients suffering from cancer disease in comparison with physiological values in healthy people. In these patients there was also found that they have higher levels of metallothionein and the ratio of GSH/GSSG was reduced. These results suggest The aim of this study was to investigate the interaction between lead ions and ethylenediaminetetraacetic acid (EDTA) in plasma. EDTA is widely used in medicine as anticoagulant agent. Understanding of the influence of EDTA on the electrochemical lead ions determination is very suitable for the determination of lead ions at patients with increased metals levels in body fluids. Further, the changes of metal ions levels (Zn, Cd, Pb and Cu) were monitored in the blood plasma of child patients treated for various oncological diseases. Electrochemical method differential pulse voltammetry with fully automated system and atomic absorption spectrometry was used for determination of the metal ions. It was found an increased amount of metal ions in the blood plasma of patients suffering from cancer disease in comparison with physiological values in healthy people. In these patients there was also found that they have higher levels of metallothionein and the ratio of GSH/GSSG was reduced. These results suggest
dcterms:title
Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry
skos:prefLabel
Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry Determination of Metal Ions in the Plasma of Children with Tumour Diseases by Differential Pulse Voltammetry
skos:notation
RIV/00216305:26620/14:PU111696!RIV15-MSM-26620___
n3:aktivita
n5:O n5:P n5:I
n3:aktivity
I, O, P(ED1.1.00/02.0068)
n3:cisloPeriodika
8
n3:dodaniDat
n14:2015
n3:domaciTvurceVysledku
n4:4733029 n4:1545515 n4:8541698 n4:4489705 n4:2307049 n4:4995775 n4:5028361
n3:druhVysledku
n17:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
10792
n3:idVysledku
RIV/00216305:26620/14:PU111696
n3:jazykVysledku
n11:eng
n3:klicovaSlova
Metals, Electrochemical Analysis, Plasma, EDTA, Interaction, Oncological Diseases
n3:klicoveSlovo
n6:Electrochemical%20Analysis n6:EDTA n6:Oncological%20Diseases n6:Interaction n6:Plasma n6:Metals
n3:kodStatuVydavatele
RS - Srbská republika
n3:kontrolniKodProRIV
[7230111E321B]
n3:nazevZdroje
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE
n3:obor
n9:JU
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
8
n3:projekt
n18:ED1.1.00%2F02.0068
n3:rokUplatneniVysledku
n14:2014
n3:svazekPeriodika
9
n3:tvurceVysledku
Kynický, Jindřich Hynek, David Novotná, Marie Eckschlager, Tomáš Kenšová, Renáta Adam, Vojtěch Kizek, René Hubálek, Jaromír
s:issn
1452-3981
s:numberOfPages
17
n12:organizacniJednotka
26620