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Statements

Subject Item
n2:RIV%2F00216305%3A26620%2F13%3APU104845%21RIV15-MSM-26620___
rdf:type
skos:Concept n16:Vysledek
rdfs:seeAlso
http://web2.mendelu.cz/af_239_nanotech/data/pub/Kizek%20from%20978-1-62948-057-2.pdf
dcterms:description
Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure. Application of electrochemical methods for protein determination was discovered in the thirties of the last century. Rudolf Brdicka was one who focused his attention to the protein electrochemical determination and used discovered analytical method for clinical purposes. Brdicka way of protein detection was based on the specific reaction between thiol group of proteins with Brdicka solution. Metallothionein (MT) as a low-molecular mass protein with high thiols content seems to be ideal target for such detection. This protein is involved in heavy metals homeostasis due to their chelation centers in MT structure.
dcterms:title
Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction
skos:prefLabel
Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction Automatized determination of metallothionein by adsorptive transfer stripping technique coupled with Brdicka reaction
skos:notation
RIV/00216305:26620/13:PU104845!RIV15-MSM-26620___
n4:aktivita
n20:P
n4:aktivity
P(ED1.1.00/02.0068)
n4:dodaniDat
n7:2015
n4:domaciTvurceVysledku
n5:4489705 n5:8541698 n5:6044786 n5:3790185 n5:4995775 n5:2307049
n4:druhVysledku
n14:C
n4:duvernostUdaju
n8:S
n4:entitaPredkladatele
n19:predkladatel
n4:idSjednocenehoVysledku
62665
n4:idVysledku
RIV/00216305:26620/13:PU104845
n4:jazykVysledku
n17:eng
n4:klicovaSlova
metallothionein, Brdicka reaction, thiol compound, mercury electrode, tumour diseases, automation
n4:klicoveSlovo
n13:mercury%20electrode n13:Brdicka%20reaction n13:thiol%20compound n13:tumour%20diseases n13:automation n13:metallothionein
n4:kontrolniKodProRIV
[70D4F1314735]
n4:mistoVydani
Neuveden
n4:nazevEdiceCisloSvazku
Neuveden
n4:nazevZdroje
Voltammetry: Theory, Types and Applications
n4:obor
n12:CG
n4:pocetDomacichTvurcuVysledku
6
n4:pocetStranKnihy
349
n4:pocetTvurcuVysledku
6
n4:projekt
n9:ED1.1.00%2F02.0068
n4:rokUplatneniVysledku
n7:2013
n4:tvurceVysledku
Tmejová, Kateřina Kizek, René Trnková, Libuše Adam, Vojtěch Hynek, David Hubálek, Jaromír
s:numberOfPages
12
n3:hasPublisher
Nova Science Publisher, Inc.
n21:isbn
978-1-62948-057-2
n18:organizacniJednotka
26620