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Statements

Subject Item
n2:RIV%2F00216305%3A26620%2F13%3APU103101%21RIV14-GA0-26620___
rdf:type
skos:Concept n9:Vysledek
dcterms:description
More surprising are the findings that levels of various miRNAs are well correlated with presence of specific tumours and formation of metastases. Moreover, these small regulatory molecules play a role in the resistance of cancer cells to commonly used anti-cancer drugs, such as cisplatin, anthracyclines, and taxanes. In that respect, miRNAs become very attractive target for potential therapeutic interventions More surprising are the findings that levels of various miRNAs are well correlated with presence of specific tumours and formation of metastases. Moreover, these small regulatory molecules play a role in the resistance of cancer cells to commonly used anti-cancer drugs, such as cisplatin, anthracyclines, and taxanes. In that respect, miRNAs become very attractive target for potential therapeutic interventions
dcterms:title
Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs. Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs.
skos:prefLabel
Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs. Prostate cancer, miRNAs, metallothioneins and resistance to cytostatic drugs.
skos:notation
RIV/00216305:26620/13:PU103101!RIV14-GA0-26620___
n9:predkladatel
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n3:aktivita
n17:P
n3:aktivity
P(ED1.1.00/02.0068), P(GAP102/11/1068), P(KAN208130801)
n3:cisloPeriodika
4
n3:dodaniDat
n6:2014
n3:domaciTvurceVysledku
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n15:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
100464
n3:idVysledku
RIV/00216305:26620/13:PU103101
n3:jazykVysledku
n18:eng
n3:klicovaSlova
Prostate carcinoma, markers, miRNA, circulating miRNAs, metallothionein, anti-cancer drugs, platinum based cytostatics, zinc, resistance, metastases.
n3:klicoveSlovo
n5:circulating%20miRNAs n5:resistance n5:metastases. n5:miRNA n5:metallothionein n5:markers n5:platinum%20based%20cytostatics n5:zinc n5:Prostate%20carcinoma n5:anti-cancer%20drugs
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[79BD670E8CA7]
n3:nazevZdroje
CURRENT MEDICINAL CHEMISTRY
n3:obor
n19:FD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:projekt
n14:ED1.1.00%2F02.0068 n14:KAN208130801 n14:GAP102%2F11%2F1068
n3:rokUplatneniVysledku
n6:2013
n3:svazekPeriodika
20
n3:tvurceVysledku
Pekařík, Vladimír Masařík, Michal Gumulec, Jaromír Kizek, René Adam, Vojtěch
s:issn
0929-8673
s:numberOfPages
11
n13:organizacniJednotka
26620