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Statements

Subject Item
n2:RIV%2F00216305%3A26310%2F05%3APU53136%21RIV06-MSM-26310___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Copolymers of lactic and glycolic acid have been recognized as biocompatible, bioresorbable and biodegradable polymers. Nowadays, these compounds are used as controlled drug delivery systems and also as materials for surgical sutures and osteosynthesis. An important property of these polymers is the possibility of modulation of their life-time and/or their physical properties by changing their composition. The importance and application range of these materials have been increasing gradually. Nevertheleess, in spite of the fact that the degradation mechanism of these copolymers has been a subject of numerous studies, it is not fully understood till now, because the results of various degradation studies are somewhat unclear and in some cases even controversial. The aim of this study was the elucidation of the degradation pathways and environmental impact of degradation products of special well-defined %22smart%22 amphiphilic, end-functionalized hydrogels prepared from biodegradable and biocompatible mon Copolymers of lactic and glycolic acid have been recognized as biocompatible, bioresorbable and biodegradable polymers. Nowadays, these compounds are used as controlled drug delivery systems and also as materials for surgical sutures and osteosynthesis. An important property of these polymers is the possibility of modulation of their life-time and/or their physical properties by changing their composition. The importance and application range of these materials have been increasing gradually. Nevertheleess, in spite of the fact that the degradation mechanism of these copolymers has been a subject of numerous studies, it is not fully understood till now, because the results of various degradation studies are somewhat unclear and in some cases even controversial. The aim of this study was the elucidation of the degradation pathways and environmental impact of degradation products of special well-defined %22smart%22 amphiphilic, end-functionalized hydrogels prepared from biodegradable and biocompatible mon Kopolymery kyseliny mléčné a glykolové byly popsány jako biokompatibilní, bioresorbovatelné a biodegradovatelné polymery. V současnosti jsou tyto polymery využívány jako systémy pro řízené dávkování léčiv a také jako materiály pro sešívání při chirurgii a pro osteosyntézu. Významnou vlastností těchto polymerů je možnost řízení doby jejich života a jejich vlastností prostřednictvím složení. Význam a rozsah využitelnosti těchto materiálů vzrůstá, nicméně mechanismus degradace těchto polymerů nebyl dosud ddetailně objasněn, přestože již byl předmětem řady studií. Cílem této studie bylo popsání degradačních cest a environmentálního vlivu degradačních produktů přesně definovaných %22smart%22 amfifilních polymerů na bázi hydrogelů s funkcionalizovanými konci řetězců.
dcterms:title
Characterization of biocompatible hydrogels: Their degradation and environmental impact of the products Biokompatibilní hydrogely: Jejich degradace a vliv degradačních produktů na životní prostředí Characterization of biocompatible hydrogels: Their degradation and environmental impact of the products
skos:prefLabel
Characterization of biocompatible hydrogels: Their degradation and environmental impact of the products Characterization of biocompatible hydrogels: Their degradation and environmental impact of the products Biokompatibilní hydrogely: Jejich degradace a vliv degradačních produktů na životní prostředí
skos:notation
RIV/00216305:26310/05:PU53136!RIV06-MSM-26310___
n5:aktivita
n18:Z
n5:aktivity
Z(MSM0021630501)
n5:dodaniDat
n9:2006
n5:domaciTvurceVysledku
n6:3072886 n6:8551987 n6:3204731 n6:9608486 n6:8034524
n5:druhVysledku
n7:A
n5:duvernostUdaju
n13:S
n5:entitaPredkladatele
n11:predkladatel
n5:idSjednocenehoVysledku
515001
n5:idVysledku
RIV/00216305:26310/05:PU53136
n5:jazykVysledku
n8:eng
n5:klicovaSlova
hydrogel, degradation, environmental impact
n5:klicoveSlovo
n12:degradation n12:hydrogel n12:environmental%20impact
n5:kodPristupu
n10:L
n5:kontrolniKodProRIV
[6A43F8ACA22C]
n5:mistoVydani
Belgrade
n5:objednatelVyzkumneZpravy
Serbian Chemical Society
n5:obor
n16:CB
n5:pocetDomacichTvurcuVysledku
5
n5:pocetTvurcuVysledku
5
n5:rokUplatneniVysledku
n9:2005
n5:tvurceVysledku
Nová, Ludmila Vojtová, Lucy Čáslavský, Josef Jančář, Josef Vávrová, Milada
n5:verzeVyzkumneZpravy
1
n5:zamer
n14:MSM0021630501
n15:isbn
86-7132-024-3
n19:organizacniJednotka
26310