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Statements

Subject Item
n2:RIV%2F00216305%3A26220%2F13%3APU105603%21RIV14-MSM-26220___
rdf:type
skos:Concept n9:Vysledek
dcterms:description
The aim of this study was to determine whether there are differences in absolute blood flow between patients with Crohn's disease with inflammation or fibrosis using contrast-enhanced ultrasound. Eighteen patients with fibrotic disease and 19 patients with inflammation were examined. Video sequences of contrast data were analyzed using a pharmacokinetic model to extract the arterial input and tissue residue functions with a custom software, enabling calculation of the absolute values for mean transit time, blood volume and flow. Feasibility of the examination was 89%. The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group. There was no significant difference in mean transit time (3.9 vs. 5.5 s). In conclusion, absolute perfusion measurement in the gastrointestinal wall using contrast-enhanced ultrasound is feasible. There seems to be reduced blood volume and blood flow in The aim of this study was to determine whether there are differences in absolute blood flow between patients with Crohn's disease with inflammation or fibrosis using contrast-enhanced ultrasound. Eighteen patients with fibrotic disease and 19 patients with inflammation were examined. Video sequences of contrast data were analyzed using a pharmacokinetic model to extract the arterial input and tissue residue functions with a custom software, enabling calculation of the absolute values for mean transit time, blood volume and flow. Feasibility of the examination was 89%. The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group. There was no significant difference in mean transit time (3.9 vs. 5.5 s). In conclusion, absolute perfusion measurement in the gastrointestinal wall using contrast-enhanced ultrasound is feasible. There seems to be reduced blood volume and blood flow in
dcterms:title
Quantitative Contrast-Enhanced Ultrasound Comparison Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease Quantitative Contrast-Enhanced Ultrasound Comparison Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease
skos:prefLabel
Quantitative Contrast-Enhanced Ultrasound Comparison Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease Quantitative Contrast-Enhanced Ultrasound Comparison Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease
skos:notation
RIV/00216305:26220/13:PU105603!RIV14-MSM-26220___
n9:predkladatel
n18:orjk%3A26220
n3:aktivita
n5:S n5:P
n3:aktivity
P(ED1.100/02/0123), S
n3:cisloPeriodika
7
n3:dodaniDat
n7:2014
n3:domaciTvurceVysledku
n15:8655537
n3:druhVysledku
n6:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
101205
n3:idVysledku
RIV/00216305:26220/13:PU105603
n3:jazykVysledku
n13:eng
n3:klicovaSlova
Crohn's disease, Inflammatory bowel disease, Intestinal blood flow, Ultrasonography
n3:klicoveSlovo
n4:Crohn%27s%20disease n4:Intestinal%20blood%20flow n4:Inflammatory%20bowel%20disease n4:Ultrasonography
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[78551327F597]
n3:nazevZdroje
ULTRASOUND IN MEDICINE AND BIOLOGY
n3:obor
n12:JA
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
9
n3:projekt
n10:ED1.100%2F02%2F0123
n3:rokUplatneniVysledku
n7:2013
n3:svazekPeriodika
39
n3:tvurceVysledku
Taxt, Torfinn Mézl, Martin Gilja, Odd Helge Odegaard, Svein Jiřík, Radovan Nylund, Kim Leh, Sabine Hausken, Trygve Pfeffer, Frank
s:issn
0301-5629
s:numberOfPages
10
n17:organizacniJednotka
26220