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Statements

Subject Item
n2:RIV%2F00216305%3A26220%2F05%3APU50359%21RIV06-GA0-26220___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes - di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result inn pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment. Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes - di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result inn pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment. Voltage-sensitive dyes have been employed to record monophasic action potentials (MAPs) in a variety of heart preparations with results comparable to classical microelectrode method. However, still little data are available on the response of the heart muscle to the loading with the dye. One of the most consistently used dyes - di-4-ANEPPS - is employed in our laboratory to record MAPs from isolated guinea pig hearts. It is of great importance to prove that loading of the heart muscle does not result inn pharmacological or toxic effects to the preparation, since the experiments are of long duration, e.g. to prove the viability and quality of the heart at the beginning of the experiment.
dcterms:title
Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium
skos:prefLabel
Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium Effects of Voltage Sensitive Dye di-4-ANEPPS on Guinea Pig Myocardium
skos:notation
RIV/00216305:26220/05:PU50359!RIV06-GA0-26220___
n3:strany
1-1
n3:aktivita
n5:P n5:Z
n3:aktivity
P(GA102/04/0472), P(GA305/04/1385), Z(MSM0021630513)
n3:dodaniDat
n15:2006
n3:domaciTvurceVysledku
n6:4096541 n6:8088586 n6:1469517 n6:5729378
n3:druhVysledku
n21:D
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
519636
n3:idVysledku
RIV/00216305:26220/05:PU50359
n3:jazykVysledku
n19:eng
n3:klicovaSlova
Voltage-sensitive dye, monophasic action potential, heart, di-4-ANEPPS
n3:klicoveSlovo
n4:monophasic%20action%20potential n4:heart n4:Voltage-sensitive%20dye n4:di-4-ANEPPS
n3:kontrolniKodProRIV
[428A1E64F620]
n3:mistoKonaniAkce
Praha
n3:mistoVydani
Praha
n3:nazevZdroje
Proceedings of EMBEC 2005
n3:obor
n14:JD
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:projekt
n8:GA102%2F04%2F0472 n8:GA305%2F04%2F1385
n3:rokUplatneniVysledku
n15:2005
n3:tvurceVysledku
Provazník, Ivo Nováková, Marie Blaha, Milan Bardoňová, Jana
n3:typAkce
n18:WRD
n3:zahajeniAkce
2005-11-20+01:00
n3:zamer
n17:MSM0021630513
s:numberOfPages
1
n20:hasPublisher
IFBME
n13:isbn
0-7803-8894-1
n22:organizacniJednotka
26220