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Statements

Subject Item
n2:RIV%2F00216275%3A25520%2F10%3A39882887%21RIV11-MZ0-25520___
rdf:type
skos:Concept n18:Vysledek
dcterms:description
Herpetic meningoencephalitis (HME) is a rare but often lethal herpes simplex infection. Patients who survive generally retain neurological deficits. Little information is available on degree and recovery of olfactory impairment following HME. In this retrospective case series, three patients (two women, one man) who had survived HME were tested with standardized olfactory tests (Sniffin' Sticks). In conclusion, the present findings show that olfactory function is often permanently damaged in patients who have had HME. Lesions lead to various patterns of olfactory loss. Together with histological and clinical data from the literature this suggests further that the olfactory pathway plays a major role in the spread of herpetic meningoencephalitis. It also raises the question whether the olfactory epithelium serves as an entry into the brain for other pathogens. Herpetic meningoencephalitis (HME) is a rare but often lethal herpes simplex infection. Patients who survive generally retain neurological deficits. Little information is available on degree and recovery of olfactory impairment following HME. In this retrospective case series, three patients (two women, one man) who had survived HME were tested with standardized olfactory tests (Sniffin' Sticks). In conclusion, the present findings show that olfactory function is often permanently damaged in patients who have had HME. Lesions lead to various patterns of olfactory loss. Together with histological and clinical data from the literature this suggests further that the olfactory pathway plays a major role in the spread of herpetic meningoencephalitis. It also raises the question whether the olfactory epithelium serves as an entry into the brain for other pathogens.
dcterms:title
Olfactory dysfunction following herpetic meningoencephalitis Olfactory dysfunction following herpetic meningoencephalitis
skos:prefLabel
Olfactory dysfunction following herpetic meningoencephalitis Olfactory dysfunction following herpetic meningoencephalitis
skos:notation
RIV/00216275:25520/10:39882887!RIV11-MZ0-25520___
n4:aktivita
n14:P
n4:aktivity
P(1A8667)
n4:cisloPeriodika
3
n4:dodaniDat
n6:2011
n4:domaciTvurceVysledku
n15:2197189
n4:druhVysledku
n12:J
n4:duvernostUdaju
n17:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
276571
n4:idVysledku
RIV/00216275:25520/10:39882887
n4:jazykVysledku
n10:eng
n4:klicovaSlova
Ageusia; Olfaction; Taste; Meningoencephalitis; Herpes; Anosmia
n4:klicoveSlovo
n5:Olfaction n5:Herpes n5:Meningoencephalitis n5:Taste n5:Ageusia n5:Anosmia
n4:kodStatuVydavatele
DE - Spolková republika Německo
n4:kontrolniKodProRIV
[BE609E26E07E]
n4:nazevZdroje
Journal of Neurology
n4:obor
n11:FF
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
3
n4:projekt
n9:1A8667
n4:rokUplatneniVysledku
n6:2010
n4:svazekPeriodika
257
n4:tvurceVysledku
Hummel, Thomas Landis, Basile Vodička, Jan
n4:wos
000275529300021
s:issn
0340-5354
s:numberOfPages
5
n13:organizacniJednotka
25520