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Statements

Subject Item
n2:RIV%2F00216275%3A25310%2F14%3A39899346%21RIV15-MSM-25310___
rdf:type
skos:Concept n6:Vysledek
dcterms:description
Lipidomic analysis is challenging due to enormous complexity of lipid structures. The mass spectrometry (MS) plays a key role in the quantitative lipidomics either without separation (shotgun ESI-MS or MALDI-TOF) or in separation coupling with MS (mainly LC/MS and SFC/MS). Each modality can bring complementary information, which can be integrated in one overall methodology. Various quantitative LC/MS and SFC/MS approaches will be discussed as well. The goal of this work is the development of complementary nontargeted and targeted MS based method for the comprehensive characterization of biological samples, which is applied for the characterization of changes caused by the tumor growth in comparison with surrounding healthy tissues. Lipidomic analysis is challenging due to enormous complexity of lipid structures. The mass spectrometry (MS) plays a key role in the quantitative lipidomics either without separation (shotgun ESI-MS or MALDI-TOF) or in separation coupling with MS (mainly LC/MS and SFC/MS). Each modality can bring complementary information, which can be integrated in one overall methodology. Various quantitative LC/MS and SFC/MS approaches will be discussed as well. The goal of this work is the development of complementary nontargeted and targeted MS based method for the comprehensive characterization of biological samples, which is applied for the characterization of changes caused by the tumor growth in comparison with surrounding healthy tissues.
dcterms:title
LC/MS and SFC/MS in Lipidomic Analysis LC/MS and SFC/MS in Lipidomic Analysis
skos:prefLabel
LC/MS and SFC/MS in Lipidomic Analysis LC/MS and SFC/MS in Lipidomic Analysis
skos:notation
RIV/00216275:25310/14:39899346!RIV15-MSM-25310___
n4:aktivita
n16:P
n4:aktivity
P(LL1302)
n4:dodaniDat
n8:2015
n4:domaciTvurceVysledku
n5:4329082 n5:1030787 n5:8944164
n4:druhVysledku
n12:O
n4:duvernostUdaju
n10:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
25797
n4:idVysledku
RIV/00216275:25310/14:39899346
n4:jazykVysledku
n11:eng
n4:klicovaSlova
Lipidomic Analysis; SFC/MS; LC/MS
n4:klicoveSlovo
n9:LC%2FMS n9:Lipidomic%20Analysis n9:SFC%2FMS
n4:kontrolniKodProRIV
[79377834704E]
n4:obor
n17:CB
n4:pocetDomacichTvurcuVysledku
3
n4:pocetTvurcuVysledku
3
n4:projekt
n14:LL1302
n4:rokUplatneniVysledku
n8:2014
n4:tvurceVysledku
Lísa, Miroslav Holčapek, Michal Cífková, Eva
n7:organizacniJednotka
25310