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Statements

Subject Item
n2:RIV%2F00216275%3A25310%2F11%3A39892610%21RIV12-MSM-25310___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
In order to understand the dynamics of large neuronal networks, one of the challenges of nowadays neuroscience is to reach the possibility to record large ensembles of neurons simultaneously. In this context, microelectrode arrays (MEA) are gaining a rapidly growing interest. However, among several major problems, increased thermal noise becomes a limiting factor when the size of the microelectrodes becomes small and weak electrical activity has to be measured. In this work, we try to overcome this limitation by using porous microelectrode arrays. In order to combine the advantages of an overall small geometric surface with an increased active surface, standard MEAs are covered with a porous metal overlayer, obtained via the colloidal crystal templating method. Using this approach, we were able to obtain first promising results with respect to a reduction of the noise level. In order to understand the dynamics of large neuronal networks, one of the challenges of nowadays neuroscience is to reach the possibility to record large ensembles of neurons simultaneously. In this context, microelectrode arrays (MEA) are gaining a rapidly growing interest. However, among several major problems, increased thermal noise becomes a limiting factor when the size of the microelectrodes becomes small and weak electrical activity has to be measured. In this work, we try to overcome this limitation by using porous microelectrode arrays. In order to combine the advantages of an overall small geometric surface with an increased active surface, standard MEAs are covered with a porous metal overlayer, obtained via the colloidal crystal templating method. Using this approach, we were able to obtain first promising results with respect to a reduction of the noise level.
dcterms:title
Macroporous Microelectrode Arrays for Measurements with Reduced Noise Macroporous Microelectrode Arrays for Measurements with Reduced Noise
skos:prefLabel
Macroporous Microelectrode Arrays for Measurements with Reduced Noise Macroporous Microelectrode Arrays for Measurements with Reduced Noise
skos:notation
RIV/00216275:25310/11:39892610!RIV12-MSM-25310___
n11:predkladatel
n12:orjk%3A25310
n3:aktivita
n8:Z
n3:aktivity
Z(MSM0021627502)
n3:cisloPeriodika
1-2
n3:dodaniDat
n16:2012
n3:domaciTvurceVysledku
n18:9814183 n18:6143083
n3:druhVysledku
n9:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
210176
n3:idVysledku
RIV/00216275:25310/11:39892610
n3:jazykVysledku
n15:eng
n3:klicovaSlova
Thermal noise; Colloidal crystal templating; Macroporous electrodes; Microelectrode arrays
n3:klicoveSlovo
n6:Microelectrode%20arrays n6:Thermal%20noise n6:Macroporous%20electrodes n6:Colloidal%20crystal%20templating
n3:kodStatuVydavatele
CH - Švýcarská konfederace
n3:kontrolniKodProRIV
[8ED5DE56936C]
n3:nazevZdroje
Journal of Electroanalytical Chemistry
n3:obor
n20:CG
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n16:2011
n3:svazekPeriodika
656
n3:tvurceVysledku
Urbanová, Veronika Li, Yanling Yvert, Blaise Vytřas, Karel Kuhn, Alexander
n3:wos
000291768300014
n3:zamer
n14:MSM0021627502
s:issn
1572-6657
s:numberOfPages
5
n10:doi
10.1016/j.jelechem.2011.01.004
n17:organizacniJednotka
25310