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Statements

Subject Item
n2:RIV%2F00216224%3A14740%2F14%3A00079334%21RIV15-MSM-14740___
rdf:type
skos:Concept n16:Vysledek
rdfs:seeAlso
http://www.dovepress.com/sensory-disturbances-inhibitory-deficits-and-the-p50-wave-in-schizophr-peer-reviewed-article-NDT
dcterms:description
Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brain to inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or %22gate%22, irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas. Sensory gating disturbances in schizophrenia are often described as an inability to filter redundant sensory stimuli that typically manifest as inability to gate neuronal responses related to the P50 wave, characterizing a decreased ability of the brain to inhibit various responses to insignificant stimuli. It implicates various deficits of perceptual and attentional functions, and this inability to inhibit, or %22gate%22, irrelevant sensory inputs leads to sensory and information overload that also may result in neuronal hyperexcitability related to disturbances of habituation mechanisms. These findings seem to be particularly important in the context of modern electrophysiological and neuroimaging data suggesting that the filtering deficits in schizophrenia are likely related to deficits in the integrity of connections between various brain areas.
dcterms:title
Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia
skos:prefLabel
Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia Sensory disturbances, inhibitory deficits, and the P50 wave in schizophrenia
skos:notation
RIV/00216224:14740/14:00079334!RIV15-MSM-14740___
n3:aktivita
n14:P n14:I
n3:aktivity
I, P(ED1.1.00/02.0068), P(LH11032)
n3:cisloPeriodika
July
n3:dodaniDat
n7:2015
n3:domaciTvurceVysledku
n11:4070550
n3:druhVysledku
n18:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
44476
n3:idVysledku
RIV/00216224:14740/14:00079334
n3:jazykVysledku
n17:eng
n3:klicovaSlova
event-related potential; information overload; inhibition; P50 wave; schizophrenia; splitting
n3:klicoveSlovo
n6:schizophrenia n6:P50%20wave n6:information%20overload n6:inhibition n6:splitting n6:event-related%20potential
n3:kodStatuVydavatele
NZ - Nový Zéland
n3:kontrolniKodProRIV
[485803F3B278]
n3:nazevZdroje
NEUROPSYCHIATRIC DISEASE AND TREATMENT
n3:obor
n19:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
3
n3:projekt
n10:ED1.1.00%2F02.0068 n10:LH11032
n3:rokUplatneniVysledku
n7:2014
n3:svazekPeriodika
10
n3:tvurceVysledku
Vlček, Přemysl Raboch, Jiří Bob, Petr
n3:wos
000339065100001
s:issn
1178-2021
s:numberOfPages
7
n12:doi
10.2147/NDT.S64219
n13:organizacniJednotka
14740