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Statements

Subject Item
n2:RIV%2F00216224%3A14740%2F14%3A00078425%21RIV15-MSM-14740___
rdf:type
skos:Concept n16:Vysledek
rdfs:seeAlso
http://ac.els-cdn.com/S0920121114001673/1-s2.0-S0920121114001673-main.pdf?_tid=797862f4-9d92-11e4-a812-00000aacb35e&acdnat=1421421495_c68d82fef4a0e8b698546a7eb04d88a5
dcterms:description
Objective: To assess changes in the relative lateralization of interictal epileptiform discharges (IEDs) and interictal EEG prognostic value in terms of surgical outcome between periods with full medication (FMP) and reduced medication (RMP) in patients with temporal lobe epilepsy (TLE) associated with hippocampal sclerosis (HS). Methods: Interictal scalp EEGs of 43 patients were evaluated for the presence of IEDs separately in a waking state (WS) and sleeping state (SS) during FMP and RMP. In each period, patients were categorized as having unitemporal or bitemporal IEDs. Surgical outcome was classified at year 1 after surgery and at last follow-up visit as Engel I or Engel II-IV; and alternatively as completely seizure-free or not seizure-free. Results: There were significant changes in relative IED lateralization between FMP and RMP during SS. The representation of patients with unitemporal IEDs declined from 37 (86%) in FMP during SS to 25 (58%) in RMP during SS (p = 0.003). Objective: To assess changes in the relative lateralization of interictal epileptiform discharges (IEDs) and interictal EEG prognostic value in terms of surgical outcome between periods with full medication (FMP) and reduced medication (RMP) in patients with temporal lobe epilepsy (TLE) associated with hippocampal sclerosis (HS). Methods: Interictal scalp EEGs of 43 patients were evaluated for the presence of IEDs separately in a waking state (WS) and sleeping state (SS) during FMP and RMP. In each period, patients were categorized as having unitemporal or bitemporal IEDs. Surgical outcome was classified at year 1 after surgery and at last follow-up visit as Engel I or Engel II-IV; and alternatively as completely seizure-free or not seizure-free. Results: There were significant changes in relative IED lateralization between FMP and RMP during SS. The representation of patients with unitemporal IEDs declined from 37 (86%) in FMP during SS to 25 (58%) in RMP during SS (p = 0.003).
dcterms:title
Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis
skos:prefLabel
Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis Effect of partial drug withdrawal on the lateralization of interictal epileptiform discharges and its relationship to surgical outcome in patients with hippocampal sclerosis
skos:notation
RIV/00216224:14740/14:00078425!RIV15-MSM-14740___
n3:aktivita
n19:P
n3:aktivity
P(ED1.1.00/02.0068)
n3:cisloPeriodika
8
n3:dodaniDat
n12:2015
n3:domaciTvurceVysledku
n6:9404457 n6:2440830 n6:3864871 n6:8132208 n6:2299690
n3:druhVysledku
n20:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
13438
n3:idVysledku
RIV/00216224:14740/14:00078425
n3:jazykVysledku
n7:eng
n3:klicovaSlova
Epilepsy; Hippocampal sclerosis; Outcome; Interictal epileptiform discharges (IEDs); Unitemporal IEDs; Bitemporal IEDs
n3:klicoveSlovo
n4:Unitemporal%20IEDs n4:Bitemporal%20IEDs n4:Outcome n4:Hippocampal%20sclerosis n4:Interictal%20epileptiform%20discharges%20%28IEDs%29 n4:Epilepsy
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[C3C70D0407A9]
n3:nazevZdroje
Epilepsy Research
n3:obor
n5:FH
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:projekt
n18:ED1.1.00%2F02.0068
n3:rokUplatneniVysledku
n12:2014
n3:svazekPeriodika
108
n3:tvurceVysledku
Kuba, Robert Janoušová, Eva Brázdil, Milan Doležalová, Irena Hermanová, Markéta
n3:wos
000342269000018
s:issn
0920-1211
s:numberOfPages
11
n15:doi
10.1016/j.eplepsyres.2014.06.009
n14:organizacniJednotka
14740