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Statements

Subject Item
n2:RIV%2F00216224%3A14740%2F14%3A00074401%21RIV15-MSM-14740___
rdf:type
skos:Concept n15:Vysledek
rdfs:seeAlso
http://www.karger.com/Article/Pdf/360775
dcterms:description
As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel
dcterms:title
Epigenetic Regulation of Telomere Maintenance Epigenetic Regulation of Telomere Maintenance
skos:prefLabel
Epigenetic Regulation of Telomere Maintenance Epigenetic Regulation of Telomere Maintenance
skos:notation
RIV/00216224:14740/14:00074401!RIV15-MSM-14740___
n3:aktivita
n4:P n4:I
n3:aktivity
I, P(ED1.1.00/02.0068), P(EE2.3.20.0043), P(EE2.3.20.0189), P(GAP501/11/0289), P(GAP501/11/0596)
n3:cisloPeriodika
1-3
n3:dodaniDat
n11:2015
n3:domaciTvurceVysledku
n13:3129888 n13:8202575
n3:druhVysledku
n18:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
14854
n3:idVysledku
RIV/00216224:14740/14:00074401
n3:jazykVysledku
n7:eng
n3:klicovaSlova
Chromatin; DNA methylation; Epigenetics; Histone modifications; Telomerase; Telomere; Telomeric transcripts
n3:klicoveSlovo
n8:Telomeric%20transcripts n8:DNA%20methylation n8:Telomerase n8:Epigenetics n8:Histone%20modifications n8:Chromatin n8:Telomere
n3:kodStatuVydavatele
CH - Švýcarská konfederace
n3:kontrolniKodProRIV
[ACF12DCFDA70]
n3:nazevZdroje
Cytogenetic and Genome research
n3:obor
n10:EB
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
2
n3:projekt
n9:EE2.3.20.0189 n9:EE2.3.20.0043 n9:ED1.1.00%2F02.0068 n9:GAP501%2F11%2F0289 n9:GAP501%2F11%2F0596
n3:rokUplatneniVysledku
n11:2014
n3:svazekPeriodika
143
n3:tvurceVysledku
Fajkus, Jiří Fojtová, Miloslava
n3:wos
000342614100013
s:issn
1424-8581
s:numberOfPages
11
n19:doi
10.1159/000360775
n14:organizacniJednotka
14740