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Statements

Subject Item
n2:RIV%2F00216224%3A14330%2F02%3A00006557%21RIV11-AV0-14330___
rdf:type
n13:Vysledek skos:Concept
dcterms:description
The spatial arrangement of some genetic elements relative to chromosome territories and in parallel with the cell nucleus was investigated in human lymphocytes. The structure of the chromosome territories was studied in chromosomes containing regions (clusters) of highly expressed genes (HSA 9, 17) and those without such clusters (HSA 8, 13). In chromosomes containing highly expressed regions, the elements pertaining to these regions were found close to the centre of the nucleus on the inner sides of chromosome territories; those pertaining to regions with low expression were localized close to the nuclear membrane on the opposite sides of the territories. In chromosomes with generally low expression (HSA 8, 13), the elements investigated were found symmetrically distributed over the territories. The spatial arrangement of some genetic elements relative to chromosome territories and in parallel with the cell nucleus was investigated in human lymphocytes. The structure of the chromosome territories was studied in chromosomes containing regions (clusters) of highly expressed genes (HSA 9, 17) and those without such clusters (HSA 8, 13). In chromosomes containing highly expressed regions, the elements pertaining to these regions were found close to the centre of the nucleus on the inner sides of chromosome territories; those pertaining to regions with low expression were localized close to the nuclear membrane on the opposite sides of the territories. In chromosomes with generally low expression (HSA 8, 13), the elements investigated were found symmetrically distributed over the territories.
dcterms:title
The 3D structure of human chromosomes in cell nuclei The 3D structure of human chromosomes in cell nuclei
skos:prefLabel
The 3D structure of human chromosomes in cell nuclei The 3D structure of human chromosomes in cell nuclei
skos:notation
RIV/00216224:14330/02:00006557!RIV11-AV0-14330___
n3:aktivita
n8:P n8:Z
n3:aktivity
P(GA202/01/0197), P(GA301/01/0186), P(IAA1065203), P(IBS5004010), P(NC5955), Z(AV0Z5004920), Z(MSM 143300002)
n3:cisloPeriodika
7
n3:dodaniDat
n16:2011
n3:domaciTvurceVysledku
n15:5810655 n15:8491313 n15:5014409 n15:1270494 n15:3021475
n3:druhVysledku
n11:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
671950
n3:idVysledku
RIV/00216224:14330/02:00006557
n3:jazykVysledku
n18:eng
n3:klicovaSlova
chromosome structure; confocal microscopy; mathematical models; nuclear architecture
n3:klicoveSlovo
n6:nuclear%20architecture n6:confocal%20microscopy n6:chromosome%20structure n6:mathematical%20models
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[B2312DE92203]
n3:nazevZdroje
Chromosome Research
n3:obor
n17:EB
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:projekt
n10:IBS5004010 n10:IAA1065203 n10:NC5955 n10:GA301%2F01%2F0186 n10:GA202%2F01%2F0197
n3:rokUplatneniVysledku
n16:2002
n3:svazekPeriodika
10
n3:tvurceVysledku
Kozubek, Stanislav Lukášová, Emilie Falk, Martin Amrichová, Jana Kozubek, Michal
n3:zamer
n9:AV0Z5004920 n9:MSM%20143300002
s:issn
0967-3849
s:numberOfPages
14
n19:organizacniJednotka
14330