This HTML5 document contains 57 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n19http://linked.opendata.cz/ontology/domain/vavai/riv/typAkce/
dctermshttp://purl.org/dc/terms/
n21http://localhost/temp/predkladatel/
n16http://purl.org/net/nknouf/ns/bibtex#
n7http://linked.opendata.cz/resource/domain/vavai/projekt/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n18http://linked.opendata.cz/ontology/domain/vavai/
n13https://schema.org/
n12http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
skoshttp://www.w3.org/2004/02/skos/core#
n9http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14330%2F02%3A00006233%21RIV08-AV0-14330___/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n11http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n5http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n22http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n20http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14330%2F02%3A00006233%21RIV08-AV0-14330___
rdf:type
skos:Concept n18:Vysledek
dcterms:description
Nuclear location of subtelomeric and centromeric DNA sequences of chromosome 8, 9 and 13 was investigated in 3D fixed human G0 and stimulated T-lymphocytes using repeated dual colour FISH. In the first hybridisation, DNA probes for p and q arms labelled by different fluorochromes were used. The centromere and the chromosome territory of the same chromosome were visualised in the second hybridisation on the same nuclei. It was found for all investigated chromosomes that contrary to centromeres located in the proximity of the nuclear membrane, the telomeres adopt more central position. These results indicate a hairpin like structure of chromosomes in the interphase nucleus. The results of this study provide information not only on the topography of subtelomeres but also images of the spatial arrangement and orientation of interphase chromosomes in cycling and non-cycling cell nuclei. Nuclear location of subtelomeric and centromeric DNA sequences of chromosome 8, 9 and 13 was investigated in 3D fixed human G0 and stimulated T-lymphocytes using repeated dual colour FISH. In the first hybridisation, DNA probes for p and q arms labelled by different fluorochromes were used. The centromere and the chromosome territory of the same chromosome were visualised in the second hybridisation on the same nuclei. It was found for all investigated chromosomes that contrary to centromeres located in the proximity of the nuclear membrane, the telomeres adopt more central position. These results indicate a hairpin like structure of chromosomes in the interphase nucleus. The results of this study provide information not only on the topography of subtelomeres but also images of the spatial arrangement and orientation of interphase chromosomes in cycling and non-cycling cell nuclei. Nuclear location of subtelomeric and centromeric DNA sequences of chromosome 8, 9 and 13 was investigated in 3D fixed human G0 and stimulated T-lymphocytes using repeated dual colour FISH. In the first hybridisation, DNA probes for p and q arms labelled by different fluorochromes were used. The centromere and the chromosome territory of the same chromosome were visualised in the second hybridisation on the same nuclei. It was found for all investigated chromosomes that contrary to centromeres located in the proximity of the nuclear membrane, the telomeres adopt more central position. These results indicate a hairpin like structure of chromosomes in the interphase nucleus. The results of this study provide information not only on the topography of subtelomeres but also images of the spatial arrangement and orientation of interphase chromosomes in cycling and non-cycling cell nuclei.
dcterms:title
Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes
skos:prefLabel
Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes Spatial distribution of centromeric and subtelomeric DNA sequences in interphase nuclei of human Go and stimulated lymphocytes
skos:notation
RIV/00216224:14330/02:00006233!RIV08-AV0-14330___
n4:strany
1
n4:aktivita
n22:P n22:Z
n4:aktivity
P(GA202/01/0197), P(GA301/01/0186), P(IAA1065203), P(NC5955), Z(MSM 143300002)
n4:dodaniDat
n20:2008
n4:domaciTvurceVysledku
n6:1270494 n6:5014409 n6:8652589 n6:3021475 n6:8491313
n4:druhVysledku
n15:D
n4:duvernostUdaju
n5:S
n4:entitaPredkladatele
n9:predkladatel
n4:idSjednocenehoVysledku
664435
n4:idVysledku
RIV/00216224:14330/02:00006233
n4:jazykVysledku
n17:eng
n4:klicovaSlova
telomere; centromere; interpahse nuclei; chromatin structure
n4:klicoveSlovo
n11:centromere n11:interpahse%20nuclei n11:chromatin%20structure n11:telomere
n4:kontrolniKodProRIV
[E6F21599B0DE]
n4:mistoKonaniAkce
15-17.10.2001, Hlohovec
n4:mistoVydani
Brno
n4:nazevZdroje
Biophysics of the genome and its interactions
n4:obor
n14:EB
n4:pocetDomacichTvurcuVysledku
5
n4:pocetTvurcuVysledku
5
n4:projekt
n7:GA202%2F01%2F0197 n7:NC5955 n7:IAA1065203 n7:GA301%2F01%2F0186
n4:rokUplatneniVysledku
n20:2002
n4:tvurceVysledku
Kozubek, Stanislav Kozubek, Michal Gajdušková, Pavla Amrichová, Jana Lukášová, Emilie
n4:typAkce
n19:EUR
n4:zahajeniAkce
2001-01-01+01:00
n4:zamer
n12:MSM%20143300002
s:numberOfPages
6
n16:hasPublisher
Masaryk University
n13:isbn
80-210-2853-X
n21:organizacniJednotka
14330