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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F13%3A00066900%21RIV14-MSM-14310___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
Hematophagous parasites have to avoid the host's hemostasis (blood coagulation) to facilitate blood intake. Therefore, they release anticoagulant peptides and anti-platelet aggregation agents into the site of feeding. These are usually produced by specialized glands and inhibit thrombosis and clot formation in the host. Antihemostatic molecules often act as protease inhibitors that target one or more serine proteases comprising the coagulation cascade. Protease inhibitors can be involved also in regulation of other biological processes, e.g., the course of host immune response. Transcriptome project on the haematophagous diplozoid monogenean Eudiplozoon nipponicum rendered view on the spectrum of bioactive molecules which can be involved in manipulation of host’s physiological processes by the parasite. Hematophagous parasites have to avoid the host's hemostasis (blood coagulation) to facilitate blood intake. Therefore, they release anticoagulant peptides and anti-platelet aggregation agents into the site of feeding. These are usually produced by specialized glands and inhibit thrombosis and clot formation in the host. Antihemostatic molecules often act as protease inhibitors that target one or more serine proteases comprising the coagulation cascade. Protease inhibitors can be involved also in regulation of other biological processes, e.g., the course of host immune response. Transcriptome project on the haematophagous diplozoid monogenean Eudiplozoon nipponicum rendered view on the spectrum of bioactive molecules which can be involved in manipulation of host’s physiological processes by the parasite.
dcterms:title
Monogenean bioactive molecules at the parasite-host interface Monogenean bioactive molecules at the parasite-host interface
skos:prefLabel
Monogenean bioactive molecules at the parasite-host interface Monogenean bioactive molecules at the parasite-host interface
skos:notation
RIV/00216224:14310/13:00066900!RIV14-MSM-14310___
n5:predkladatel
n16:orjk%3A14310
n3:aktivita
n10:S n10:P
n3:aktivity
P(GAP506/12/1258), S
n3:dodaniDat
n9:2014
n3:domaciTvurceVysledku
n4:4591704 n4:2900041 n4:1604422
n3:druhVysledku
n13:O
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
89485
n3:idVysledku
RIV/00216224:14310/13:00066900
n3:jazykVysledku
n11:eng
n3:klicovaSlova
trancriptome; blood-feeding; monogeneans; anticoagulant peptides
n3:klicoveSlovo
n14:anticoagulant%20peptides n14:blood-feeding n14:monogeneans n14:trancriptome
n3:kontrolniKodProRIV
[5BDBEC5A5A4C]
n3:obor
n12:EG
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
7
n3:projekt
n15:GAP506%2F12%2F1258
n3:rokUplatneniVysledku
n9:2013
n3:tvurceVysledku
Gelnar, Milan Kašný, Martin Ilgová, Jana Jedličková, Lucie Mikeš, Libor Skipalová, Karolína Dvořáková, Hana
n8:organizacniJednotka
14310