This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n17http://localhost/temp/predkladatel/
n14http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n9http://linked.opendata.cz/resource/domain/vavai/projekt/
n18http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14310%2F12%3A00067589%21RIV14-MSM-14310___/
n12http://linked.opendata.cz/resource/domain/vavai/subjekt/
n11http://linked.opendata.cz/ontology/domain/vavai/
n5http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
n19http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n6http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n21http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n20http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n15http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F12%3A00067589%21RIV14-MSM-14310___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Background. Experimental, epidemiological and clinical data substantiate the beneficial role of n-3 polyunsaturated fatty acids (PUFAs) in preventing inflammation and cancer of the colon. This review covers the unsaturated docosahexaenoic fatty acid (DHA), describes some of its important cellular and molecular mechanisms, its interaction with another dietary lipid, butyrate and with endogenous apoptotic regulators of the tumour necrosis factor (TNF) family. We also discuss the clinical impact of this knowledge and the use of these lipids in colon cancer prevention and treatment. Results. From the literature, DHA has been shown to suppress the growth, induce apoptosis in colon cancer cells in vitro and decrease the incidence and growth of experimental tumours in vivo. Based on these data and our own experimental results, we describe and discuss the possible mechanisms of DHA anticancer effects at various levels of cell organization. Background. Experimental, epidemiological and clinical data substantiate the beneficial role of n-3 polyunsaturated fatty acids (PUFAs) in preventing inflammation and cancer of the colon. This review covers the unsaturated docosahexaenoic fatty acid (DHA), describes some of its important cellular and molecular mechanisms, its interaction with another dietary lipid, butyrate and with endogenous apoptotic regulators of the tumour necrosis factor (TNF) family. We also discuss the clinical impact of this knowledge and the use of these lipids in colon cancer prevention and treatment. Results. From the literature, DHA has been shown to suppress the growth, induce apoptosis in colon cancer cells in vitro and decrease the incidence and growth of experimental tumours in vivo. Based on these data and our own experimental results, we describe and discuss the possible mechanisms of DHA anticancer effects at various levels of cell organization.
dcterms:title
Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review
skos:prefLabel
Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review Docosahexaenoic fatty acid (DHA) in the regulation of colon cell growth and cell death: A review
skos:notation
RIV/00216224:14310/12:00067589!RIV14-MSM-14310___
n11:predkladatel
n12:orjk%3A14310
n4:aktivita
n13:Z n13:S n13:P n13:I
n4:aktivity
I, P(GAP301/11/1730), P(GD303/09/H048), S, Z(AV0Z50040702), Z(MSM0021622430)
n4:cisloPeriodika
3
n4:dodaniDat
n15:2014
n4:domaciTvurceVysledku
n14:1075020
n4:druhVysledku
n21:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n18:predkladatel
n4:idSjednocenehoVysledku
131826
n4:idVysledku
RIV/00216224:14310/12:00067589
n4:jazykVysledku
n16:eng
n4:klicovaSlova
polyunsaturated fatty acids; docosahexaenoic acid; colon cancer; apoptosis; cell signalling; anticancer therapy
n4:klicoveSlovo
n7:apoptosis n7:anticancer%20therapy n7:cell%20signalling n7:polyunsaturated%20fatty%20acids n7:docosahexaenoic%20acid n7:colon%20cancer
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[B858FCBEA50B]
n4:nazevZdroje
BIOMEDICAL PAPERS-OLOMOUC
n4:obor
n20:ED
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
3
n4:projekt
n9:GD303%2F09%2FH048 n9:GAP301%2F11%2F1730
n4:rokUplatneniVysledku
n15:2012
n4:svazekPeriodika
156
n4:tvurceVysledku
Skender, Belma Vaculová Hyršlová, Alena Hofmanová, Jiřina
n4:wos
000310725900001
n4:zamer
n5:MSM0021622430 n5:AV0Z50040702
s:issn
1213-8118
s:numberOfPages
14
n19:doi
10.5507/bp.2012.093
n17:organizacniJednotka
14310