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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F12%3A00059320%21RIV13-MSM-14310___
rdf:type
n6:Vysledek skos:Concept
dcterms:description
The proposed research is to select and set up a battery of biomarkers to be applied on the wax moth (Galleria mellonella) as an environmental indicator for assessing the toxicity of cadmium-contaminated areas. This insect specie is traditionally used as a model in many biological and ecological studies because of its easiness breeding in laboratory, repeated generations during the year and its plasticity for developing and optimizing eco-toxicological assays. It is reasonable that multiple bioassays may provide more reliable data to evaluate simultaneously the effects of the environmental conditions on several biological parameters avoiding false positive/negative results. We suppose that antioxidant and detoxification systems play an important role in the defense mechanisms against cadmium and other xenobiotics which endogenously produce reactive oxygen species (ROS) in several insects. The proposed research is to select and set up a battery of biomarkers to be applied on the wax moth (Galleria mellonella) as an environmental indicator for assessing the toxicity of cadmium-contaminated areas. This insect specie is traditionally used as a model in many biological and ecological studies because of its easiness breeding in laboratory, repeated generations during the year and its plasticity for developing and optimizing eco-toxicological assays. It is reasonable that multiple bioassays may provide more reliable data to evaluate simultaneously the effects of the environmental conditions on several biological parameters avoiding false positive/negative results. We suppose that antioxidant and detoxification systems play an important role in the defense mechanisms against cadmium and other xenobiotics which endogenously produce reactive oxygen species (ROS) in several insects.
dcterms:title
Wax moth (Galleria mellonella) as a bio-indicator model in ecotoxicological studies on cadmium Wax moth (Galleria mellonella) as a bio-indicator model in ecotoxicological studies on cadmium
skos:prefLabel
Wax moth (Galleria mellonella) as a bio-indicator model in ecotoxicological studies on cadmium Wax moth (Galleria mellonella) as a bio-indicator model in ecotoxicological studies on cadmium
skos:notation
RIV/00216224:14310/12:00059320!RIV13-MSM-14310___
n6:predkladatel
n11:orjk%3A14310
n3:aktivita
n15:S
n3:aktivity
S
n3:dodaniDat
n4:2013
n3:domaciTvurceVysledku
n9:1942859 n9:9414991 Panzarino, Onofrio n9:2304155 n9:4101197
n3:druhVysledku
n17:O
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
180756
n3:idVysledku
RIV/00216224:14310/12:00059320
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Cadmium; Ecotoxicology; Galleria mellonella; Antioxidants; Reactive oxygen species; Superoxide dismutase; Catalase; Glutathione-S-transferase; Malondialdehyde
n3:klicoveSlovo
n7:Catalase n7:Cadmium n7:Galleria%20mellonella n7:Malondialdehyde n7:Ecotoxicology n7:Antioxidants n7:Superoxide%20dismutase n7:Reactive%20oxygen%20species n7:Glutathione-S-transferase
n3:kontrolniKodProRIV
[A97F8A781EF6]
n3:obor
n14:EC
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:rokUplatneniVysledku
n4:2012
n3:tvurceVysledku
Vojtek, Libor Hyršl, Pavel Bari, Giuseppe Dobeš, Pavel Vostal, Karel de Lillo, Enrico Panzarino, Onofrio
n16:organizacniJednotka
14310