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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F12%3A00057616%21RIV13-GA0-14310___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Cyanobacterial blooms represent a serious threat to the aquatic environment. Among other effects, biochemical markers have been studied in aquatic vertebrates after exposures to toxic cyanobacteria. Some parameters such as protein phosphatases may serve as selective markers of exposure to microcystins, but under natural conditions, fish are exposed to complex mixtures, which affect the overall biomarker response. This review aims to provide a critical summary of biomarker responses in aquatic vertebrates (mostly fish) to toxic cyanobacteria with a special focus on detoxification and oxidative stress. Detoxification biomarkers such as glutathione (GSH) and glutathione-S-transferase (GST) showed very high variability with poor general trends. Often, stimulations and/or inhibitions and/or no effects at GSH or GST have been reported, even within a single study, depending on many variables, including time, dose, tissue, species, etc. Most of the oxidative stress biomarkers (e.g. Cyanobacterial blooms represent a serious threat to the aquatic environment. Among other effects, biochemical markers have been studied in aquatic vertebrates after exposures to toxic cyanobacteria. Some parameters such as protein phosphatases may serve as selective markers of exposure to microcystins, but under natural conditions, fish are exposed to complex mixtures, which affect the overall biomarker response. This review aims to provide a critical summary of biomarker responses in aquatic vertebrates (mostly fish) to toxic cyanobacteria with a special focus on detoxification and oxidative stress. Detoxification biomarkers such as glutathione (GSH) and glutathione-S-transferase (GST) showed very high variability with poor general trends. Often, stimulations and/or inhibitions and/or no effects at GSH or GST have been reported, even within a single study, depending on many variables, including time, dose, tissue, species, etc. Most of the oxidative stress biomarkers (e.g.
dcterms:title
Oxidative stress and detoxification biomarker responses in aquatic freshwatervertebrates exposed to microcystins and cyanobacterial biomass. Oxidative stress and detoxification biomarker responses in aquatic freshwatervertebrates exposed to microcystins and cyanobacterial biomass.
skos:prefLabel
Oxidative stress and detoxification biomarker responses in aquatic freshwatervertebrates exposed to microcystins and cyanobacterial biomass. Oxidative stress and detoxification biomarker responses in aquatic freshwatervertebrates exposed to microcystins and cyanobacterial biomass.
skos:notation
RIV/00216224:14310/12:00057616!RIV13-GA0-14310___
n12:predkladatel
n20:orjk%3A14310
n3:aktivita
n10:P n10:Z
n3:aktivity
P(ED0001/01/01), P(GAP503/12/0553), Z(MSM0021622412)
n3:cisloPeriodika
6
n3:dodaniDat
n15:2013
n3:domaciTvurceVysledku
n17:4982800 n17:7132654 n17:9372318
n3:druhVysledku
n7:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
157553
n3:idVysledku
RIV/00216224:14310/12:00057616
n3:jazykVysledku
n13:eng
n3:klicovaSlova
Biomarkers; Cyanobacteria; Detoxification; Fish; Oxidative stress; Microcystin
n3:klicoveSlovo
n5:Microcystin n5:Detoxification n5:Cyanobacteria n5:Fish n5:Biomarkers n5:Oxidative%20stress
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[295DD12CC38D]
n3:nazevZdroje
Environmental Science and Pollution Research
n3:obor
n19:DJ
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n11:GAP503%2F12%2F0553 n11:ED0001%2F01%2F01
n3:rokUplatneniVysledku
n15:2012
n3:svazekPeriodika
19
n3:tvurceVysledku
Bláha, Luděk Paskerová, Hana Hilscherová, Klára
n3:wos
000306123000016
n3:zamer
n16:MSM0021622412
s:issn
0944-1344
s:numberOfPages
14
n18:doi
10.1007/s11356-012-0960-7
n21:organizacniJednotka
14310