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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F11%3A00054375%21RIV12-MSM-14310___
rdf:type
skos:Concept n8:Vysledek
dcterms:description
In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consists in modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5]. In the last few decades nanotechnology has been bringing new possibilities for the construction of biosensors and development of new bioassays [1]. The greatest attention has been paid to gold nanoparticles (AuNPs) which, due to their good biocompatibility, conductivity and unique structural, electronic, magnetic, optical and catalytic properties, are very attractive materials for the construction of chemical sensors and biosensors [2,3]. For the study of proteins the construction of biosensors consists in modified AuNPs anchored on the surface of electrodes, aptamer bonding to the protein studied [4]. The most intensively studied aptamer is a DNA 15-mer known as thrombin binding aptamer (TBA), which binds thrombin and inhibits its activity in the formation of a blood clot [5].
dcterms:title
Gold nanoparticles modified by thrombin binding aptamer Gold nanoparticles modified by thrombin binding aptamer
skos:prefLabel
Gold nanoparticles modified by thrombin binding aptamer Gold nanoparticles modified by thrombin binding aptamer
skos:notation
RIV/00216224:14310/11:00054375!RIV12-MSM-14310___
n8:predkladatel
n9:orjk%3A14310
n3:aktivita
n11:S n11:P n11:Z
n3:aktivity
P(LC06035), S, Z(MSM0021622412)
n3:dodaniDat
n6:2012
n3:domaciTvurceVysledku
n10:3790185 n10:6359922
n3:druhVysledku
n5:O
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
201410
n3:idVysledku
RIV/00216224:14310/11:00054375
n3:jazykVysledku
n19:eng
n3:klicovaSlova
AuNPs; TBA; SAM; DNA; TEM
n3:klicoveSlovo
n12:DNA n12:AuNPs n12:SAM n12:TEM n12:TBA
n3:kontrolniKodProRIV
[CEC66ADF0F8F]
n3:obor
n16:CF
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
3
n3:projekt
n13:LC06035
n3:rokUplatneniVysledku
n6:2011
n3:tvurceVysledku
Castillo, Gabriela Trnková, Libuše Pilařová, Iveta
n3:zamer
n14:MSM0021622412
n18:organizacniJednotka
14310