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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F10%3A00045665%21RIV11-MSM-14310___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Cellular auxin levels are determined by processes including synthesis, degradation, and conjugation, as well as by auxin transport across the plasma membrane. Whereas transport of free auxins such as naturally occurring IAA is well characterized, little is known about the transport of auxin precursors and metabolites. Here, we identify amutation in the ABCG37 gene of Arabidopsis that causes the polar auxin transport inhibitor sensitive1 (pis1) phenotype manifested by hypersensitivity to auxinic compounds. ABCG37 encodes the pleiotropic drug resistance transporter that transports a range of synthetic auxinic compounds as well as the endogenous auxin precursor indole-3-butyric acid (IBA), but not free IAA. ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB families, transport IBA out of the cells. Our findings explore possible novel modes of regulating auxin homeostasis and plant development. Cellular auxin levels are determined by processes including synthesis, degradation, and conjugation, as well as by auxin transport across the plasma membrane. Whereas transport of free auxins such as naturally occurring IAA is well characterized, little is known about the transport of auxin precursors and metabolites. Here, we identify amutation in the ABCG37 gene of Arabidopsis that causes the polar auxin transport inhibitor sensitive1 (pis1) phenotype manifested by hypersensitivity to auxinic compounds. ABCG37 encodes the pleiotropic drug resistance transporter that transports a range of synthetic auxinic compounds as well as the endogenous auxin precursor indole-3-butyric acid (IBA), but not free IAA. ABCG37 and its homolog ABCG36 act redundantly at outermost root plasma membranes and, unlike established IAA transporters from the PIN and ABCB families, transport IBA out of the cells. Our findings explore possible novel modes of regulating auxin homeostasis and plant development.
dcterms:title
Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid. Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
skos:prefLabel
Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid. Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid.
skos:notation
RIV/00216224:14310/10:00045665!RIV11-MSM-14310___
n3:aktivita
n15:Z
n3:aktivity
Z(MSM0021622415)
n3:cisloPeriodika
23
n3:dodaniDat
n9:2011
n3:domaciTvurceVysledku
n16:6662072 n16:3730832 n16:8612617
n3:druhVysledku
n10:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
247609
n3:idVysledku
RIV/00216224:14310/10:00045665
n3:jazykVysledku
n11:eng
n3:klicovaSlova
pdr9; pdr8; iba transport; auxin synthesis
n3:klicoveSlovo
n5:auxin%20synthesis n5:pdr8 n5:pdr9 n5:iba%20transport
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[3516F6D2E6AA]
n3:nazevZdroje
Proceedings of the National Academy of Sciences of the U.S.A.,
n3:obor
n13:EB
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
17
n3:rokUplatneniVysledku
n9:2010
n3:svazekPeriodika
107
n3:tvurceVysledku
Hejátko, Jan Martinoia, E. Bailly, A. Murphy, A. Růžička, K. Nejedlá, Eliška Geisler, M. Itoh, H. Syono, K. Yang, H. Fujita, H. Blakeslee, J. Łangowski, Ł. Gray, W .M. Friml, Jiří Strader, L. C. Bartel, B.
n3:zamer
n18:MSM0021622415
s:issn
0027-8424
s:numberOfPages
5
n12:organizacniJednotka
14310