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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F10%3A00044713%21RIV11-GA0-14310___
rdf:type
n10:Vysledek skos:Concept
dcterms:description
LIF is a cytokine that exhibits pleiotropic activities in a wide range of cell types. there are evidences that LIF-regulated signaling pathway are involved in cardiomyogenesis. We studied the effect of LIF on cardiomyogenesis in presence of serum-born factors. We found out that LIF had an inhibitory effect during the induction and progression phases of cardiomyogenesis of mES cells. This effect was abolished by inhibitors of STAT3 activity. LIF is a cytokine that exhibits pleiotropic activities in a wide range of cell types. there are evidences that LIF-regulated signaling pathway are involved in cardiomyogenesis. We studied the effect of LIF on cardiomyogenesis in presence of serum-born factors. We found out that LIF had an inhibitory effect during the induction and progression phases of cardiomyogenesis of mES cells. This effect was abolished by inhibitors of STAT3 activity.
dcterms:title
Leukaemia Inhibitory Factor Inhibits Cardiomyogenesis of Mouse Embryonic Stem Cells via STAT3 Activation Leukaemia Inhibitory Factor Inhibits Cardiomyogenesis of Mouse Embryonic Stem Cells via STAT3 Activation
skos:prefLabel
Leukaemia Inhibitory Factor Inhibits Cardiomyogenesis of Mouse Embryonic Stem Cells via STAT3 Activation Leukaemia Inhibitory Factor Inhibits Cardiomyogenesis of Mouse Embryonic Stem Cells via STAT3 Activation
skos:notation
RIV/00216224:14310/10:00044713!RIV11-GA0-14310___
n3:aktivita
n7:V n7:S n7:P
n3:aktivity
P(GA301/08/0717), P(GD204/09/H058), S, V
n3:cisloPeriodika
56
n3:dodaniDat
n17:2011
n3:domaciTvurceVysledku
n4:3110540 n4:3283038 n4:2739011 n4:6215750
n3:druhVysledku
n14:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
268349
n3:idVysledku
RIV/00216224:14310/10:00044713
n3:jazykVysledku
n13:eng
n3:klicovaSlova
LIF; Cardiomyocytes; embryonic stem cells; STAT3
n3:klicoveSlovo
n9:LIF n9:embryonic%20stem%20cells n9:STAT3 n9:Cardiomyocytes
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[9B1868127FA6]
n3:nazevZdroje
Folia biologica
n3:obor
n18:ED
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:projekt
n8:GA301%2F08%2F0717 n8:GD204%2F09%2FH058
n3:rokUplatneniVysledku
n17:2010
n3:svazekPeriodika
neuveden
n3:tvurceVysledku
Procházková, Jiřina Pacherník, Jiří Jankovská, Štěpánka Veselá, Iva Kotasová, Hana
n3:wos
000281924500004
s:issn
0015-5500
s:numberOfPages
8
n15:organizacniJednotka
14310