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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F09%3A00037136%21RIV10-MSM-14310___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Cryptosporidia are significant vertebrate pathogens with unique invasion strategy, which, together with phylogenetic analyses suggest a close affinity to gregarines. Electron microscopic observations on 2 evolutionarily distinct gastric species, Cryptosporidium muris from experimentally infected rodents and C. fragile from naturally infected toads, allowed us to map ultrastructural aspects of the cryptosporidian invasion process along with the origin and architecture of parasitophorous sac, and to generalize these observations for gastric cryptosporidia. Both species exhibit a comparable strategy of host cell invasion in which they do not penetrate under the host cell plasma membrane, nor do they come into close contact with the host cytoplasm. Parasite remains attached to the host cell surface, only enveloped by the host membrane folds. Thus, the term epicellular more accurately defines the host compartment within which cryptosporidia reside than does the term intracellular-extracytoplasmic. Cryptosporidia are significant vertebrate pathogens with unique invasion strategy, which, together with phylogenetic analyses suggest a close affinity to gregarines. Electron microscopic observations on 2 evolutionarily distinct gastric species, Cryptosporidium muris from experimentally infected rodents and C. fragile from naturally infected toads, allowed us to map ultrastructural aspects of the cryptosporidian invasion process along with the origin and architecture of parasitophorous sac, and to generalize these observations for gastric cryptosporidia. Both species exhibit a comparable strategy of host cell invasion in which they do not penetrate under the host cell plasma membrane, nor do they come into close contact with the host cytoplasm. Parasite remains attached to the host cell surface, only enveloped by the host membrane folds. Thus, the term epicellular more accurately defines the host compartment within which cryptosporidia reside than does the term intracellular-extracytoplasmic.
dcterms:title
How do cryptosporidia establish their unique niche within the host epithelium? How do cryptosporidia establish their unique niche within the host epithelium?
skos:prefLabel
How do cryptosporidia establish their unique niche within the host epithelium? How do cryptosporidia establish their unique niche within the host epithelium?
skos:notation
RIV/00216224:14310/09:00037136!RIV10-MSM-14310___
n3:aktivita
n16:S n16:P n16:Z
n3:aktivity
P(LC522), S, Z(MSM0021622416)
n3:dodaniDat
n7:2010
n3:domaciTvurceVysledku
n4:7951302
n3:druhVysledku
n11:O
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
317847
n3:idVysledku
RIV/00216224:14310/09:00037136
n3:jazykVysledku
n10:eng
n3:klicovaSlova
Cryptosporidium; epicellular; parasite
n3:klicoveSlovo
n6:epicellular n6:parasite n6:Cryptosporidium
n3:kontrolniKodProRIV
[49CC4C6ACBD2]
n3:obor
n18:EG
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
1
n3:projekt
n17:LC522
n3:rokUplatneniVysledku
n7:2009
n3:tvurceVysledku
Valigurová, Andrea
n3:zamer
n15:MSM0021622416
n13:organizacniJednotka
14310