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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F07%3A00020383%21RIV11-GA0-14310___
rdf:type
n9:Vysledek skos:Concept
dcterms:description
In numerous studies the contamination of river sediments has been assessed both by chemical analysis and especially by bioassays from single time sampling reflecting just the actual situation. Two year study has been conducted to reveal the spatial and temporal-seasonal variability in the concentrations of commonly studied contaminants, but namely of the chemicals with specific modes of action in river sediments. Along with analysis of known pollutants we have assessed the overall potencies of the sediment extracts for cytotoxicity, dioxin-like, (anti)estrogenic and (anti)androgenic potency. Battery of in vitro bioassays with recombinant yeast and human cell systems was used to evaluate the extracts of sediments from four consequent sampling representing two different seasons. These bioassays show an integrative measure and identify the sites with continuously increased potencies for specific toxicity. In numerous studies the contamination of river sediments has been assessed both by chemical analysis and especially by bioassays from single time sampling reflecting just the actual situation. Two year study has been conducted to reveal the spatial and temporal-seasonal variability in the concentrations of commonly studied contaminants, but namely of the chemicals with specific modes of action in river sediments. Along with analysis of known pollutants we have assessed the overall potencies of the sediment extracts for cytotoxicity, dioxin-like, (anti)estrogenic and (anti)androgenic potency. Battery of in vitro bioassays with recombinant yeast and human cell systems was used to evaluate the extracts of sediments from four consequent sampling representing two different seasons. These bioassays show an integrative measure and identify the sites with continuously increased potencies for specific toxicity.
dcterms:title
Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples
skos:prefLabel
Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples
skos:notation
RIV/00216224:14310/07:00020383!RIV11-GA0-14310___
n3:aktivita
n6:P
n3:aktivity
P(GP525/05/P160)
n3:dodaniDat
n13:2011
n3:domaciTvurceVysledku
n8:9372318 n8:1189794 n8:8410720
n3:druhVysledku
n17:O
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
454524
n3:idVysledku
RIV/00216224:14310/07:00020383
n3:jazykVysledku
n15:eng
n3:klicovaSlova
in vitro bioassays; (anti)estrogenicity; (anti)androgenicity; TCDD-like activity
n3:klicoveSlovo
n4:TCDD-like%20activity n4:%28anti%29androgenicity n4:%28anti%29estrogenicity n4:in%20vitro%20bioassays
n3:kontrolniKodProRIV
[5AC8C3620D96]
n3:obor
n5:DJ
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:projekt
n12:GP525%2F05%2FP160
n3:rokUplatneniVysledku
n13:2007
n3:tvurceVysledku
Hilscherová, Klára Štěpánková, Tereza Jálová, Veronika Giesy, J.
n16:organizacniJednotka
14310