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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F07%3A00020354%21RIV10-MSM-14310___
rdf:type
skos:Concept n14:Vysledek
dcterms:description
Humic substances (HS) and natural organic matter (NOM) are natural organic compounds ubiquitous in the environment. However, some studies indicate that both HS and NOM can act as xenobiotics, e.g. induce hormone like effects in fish, amphibians and invertebrates. Molecules of these substances contain a number of aromatic rings and conjugated double bonds, the so called chromophores. Irradiation of dissolved HS and NOM can lead to a series of photochemical reactions which can act on these substances itself, or on other substances present in aquatic environment along with HS and NOM such as e.g. xenobiotics. In our previous study, we have found significant interactions of five humic acids (HA) with cytosolic aryl hydrocarbon receptor (AhR) in an in vitro bioassay based on H4IIEluc cells. In the present study, we have studied the changes in AhR mediated activities both of HS and NOM after irradiation that simulated natural solar light. Humic substances (HS) and natural organic matter (NOM) are natural organic compounds ubiquitous in the environment. However, some studies indicate that both HS and NOM can act as xenobiotics, e.g. induce hormone like effects in fish, amphibians and invertebrates. Molecules of these substances contain a number of aromatic rings and conjugated double bonds, the so called chromophores. Irradiation of dissolved HS and NOM can lead to a series of photochemical reactions which can act on these substances itself, or on other substances present in aquatic environment along with HS and NOM such as e.g. xenobiotics. In our previous study, we have found significant interactions of five humic acids (HA) with cytosolic aryl hydrocarbon receptor (AhR) in an in vitro bioassay based on H4IIEluc cells. In the present study, we have studied the changes in AhR mediated activities both of HS and NOM after irradiation that simulated natural solar light.
dcterms:title
Changes of AhR-mediated activity of humic substances after irradiation Changes of AhR-mediated activity of humic substances after irradiation
skos:prefLabel
Changes of AhR-mediated activity of humic substances after irradiation Changes of AhR-mediated activity of humic substances after irradiation
skos:notation
RIV/00216224:14310/07:00020354!RIV10-MSM-14310___
n3:aktivita
n5:P n5:Z
n3:aktivity
P(GP525/05/P160), Z(MSM0021622412)
n3:cisloPeriodika
33
n3:dodaniDat
n13:2010
n3:domaciTvurceVysledku
n9:2423685 n9:9372318
n3:druhVysledku
n18:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
413249
n3:idVysledku
RIV/00216224:14310/07:00020354
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Humic acids; Ah receptor; H4IIE-luc; Absorbance; NOM
n3:klicoveSlovo
n11:Humic%20acids n11:NOM n11:Absorbance n11:Ah%20receptor n11:H4IIE-luc
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[372EB20D9845]
n3:nazevZdroje
Environment International
n3:obor
n6:DN
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
3
n3:projekt
n15:GP525%2F05%2FP160
n3:rokUplatneniVysledku
n13:2007
n3:svazekPeriodika
33
n3:tvurceVysledku
Giesy, John Paul Hilscherová, Klára Bittner, Michal
n3:wos
000248273700013
n3:zamer
n17:MSM0021622412
s:issn
0160-4120
s:numberOfPages
6
n8:organizacniJednotka
14310