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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F05%3A00014614%21RIV10-MSM-14310___
rdf:type
n9:Vysledek skos:Concept
dcterms:description
Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA), fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progression of endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR). Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA), fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progression of endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR).
dcterms:title
Activation of AH-receptor by humic substances Activation of AH-receptor by humic substances
skos:prefLabel
Activation of AH-receptor by humic substances Activation of AH-receptor by humic substances
skos:notation
RIV/00216224:14310/05:00014614!RIV10-MSM-14310___
n3:aktivita
n4:Z n4:P
n3:aktivity
P(GP525/05/P160), Z(MSM0021622412)
n3:dodaniDat
n15:2010
n3:domaciTvurceVysledku
n7:9372318 n7:4982800 n7:6120393 n7:2423685 n7:4468503
n3:druhVysledku
n14:D
n3:duvernostUdaju
n22:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
511297
n3:idVysledku
RIV/00216224:14310/05:00014614
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Humic substances; dioxin-like activity
n3:klicoveSlovo
n10:dioxin-like%20activity n10:Humic%20substances
n3:kontrolniKodProRIV
[6833B134E042]
n3:mistoKonaniAkce
Toila. Estonsko
n3:mistoVydani
Tallinn, Estonsko
n3:nazevZdroje
Joint Conference of Scandinavian Society of Cell Toxicology and Estonian Society of Toxicology
n3:obor
n18:DN
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
6
n3:projekt
n13:GP525%2F05%2FP160
n3:rokUplatneniVysledku
n15:2005
n3:tvurceVysledku
Hilscherová, Klára Janošek, Jaroslav Bittner, Michal Bláha, Luděk Giesy, John Paul Holoubek, Ivan
n3:typAkce
n16:WRD
n3:zahajeniAkce
2005-10-20+02:00
n3:zamer
n20:MSM0021622412
s:numberOfPages
1
n19:hasPublisher
ETS-SSCT
n8:isbn
9949-13-297-5
n6:organizacniJednotka
14310