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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F04%3A00010008%21RIV08-MSM-14310___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Explicit-solvent molecular dynamics simulation is a powerful technique for exploring the functionally relevant motions in biological macromolecules and for evaluating the effects of mutations on motif dynamics. Simulation of flexible and rigid RNA motifs will be compared by detailed statistical and structural analysis. Mechanisms for modulating functionally significant flexibility will be discussed, emphasizing the role of RNA-RNA interactions mediated by solvent molecules. Explicit-solvent molecular dynamics simulation is a powerful technique for exploring the functionally relevant motions in biological macromolecules and for evaluating the effects of mutations on motif dynamics. Simulation of flexible and rigid RNA motifs will be compared by detailed statistical and structural analysis. Mechanisms for modulating functionally significant flexibility will be discussed, emphasizing the role of RNA-RNA interactions mediated by solvent molecules. Explicit-solvent molecular dynamics simulation is a powerful technique for exploring the functionally relevant motions in biological macromolecules and for evaluating the effects of mutations on motif dynamics. Simulation of flexible and rigid RNA motifs will be compared by detailed statistical and structural analysis. Mechanisms for modulating functionally significant flexibility will be discussed, emphasizing the role of RNA-RNA interactions mediated by solvent molecules.
dcterms:title
Molecular Dynamics simulations of flexible RNA motifs Molecular Dynamics simulations of flexible RNA motifs Molekulovo-dynamicka simulacia flexibilnych RNA motivov
skos:prefLabel
Molecular Dynamics simulations of flexible RNA motifs Molekulovo-dynamicka simulacia flexibilnych RNA motivov Molecular Dynamics simulations of flexible RNA motifs
skos:notation
RIV/00216224:14310/04:00010008!RIV08-MSM-14310___
n3:strany
10
n3:aktivita
n19:P
n3:aktivity
P(LN00A016)
n3:dodaniDat
n9:2008
n3:domaciTvurceVysledku
n14:4347374 n14:4585623 n14:3223779
n3:druhVysledku
n13:D
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n20:predkladatel
n3:idSjednocenehoVysledku
574369
n3:idVysledku
RIV/00216224:14310/04:00010008
n3:jazykVysledku
n17:eng
n3:klicovaSlova
RNA flexibility
n3:klicoveSlovo
n6:RNA%20flexibility
n3:kontrolniKodProRIV
[0490F2976E6C]
n3:mistoKonaniAkce
Anaheim, California, USA
n3:mistoVydani
Washington
n3:nazevZdroje
American Chemical Society Division of Computers in Chemistry
n3:obor
n7:CF
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:projekt
n15:LN00A016
n3:rokUplatneniVysledku
n9:2004
n3:tvurceVysledku
Leontis, Neocles B. Šponer, Jiří Rázga, Filip Koča, Jaroslav
n3:typAkce
n10:WRD
n3:zahajeniAkce
2004-03-28+01:00
s:numberOfPages
1
n16:hasPublisher
American Chemical Society
n18:organizacniJednotka
14310