This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

Prefix	IRI
n15	http://linked.opendata.cz/ontology/domain/vavai/riv/typAkce/
dcterms	http://purl.org/dc/terms/
n18	http://localhost/temp/predkladatel/
n12	http://purl.org/net/nknouf/ns/bibtex#
n16	http://linked.opendata.cz/resource/domain/vavai/projekt/
n10	http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n17	http://linked.opendata.cz/ontology/domain/vavai/
s	http://schema.org/
skos	http://www.w3.org/2004/02/skos/core#
n3	http://linked.opendata.cz/ontology/domain/vavai/riv/
n8	http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14310%2F03%3A00009270%21RIV08-MSM-14310___/
n2	http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#
n14	http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n20	http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdh	http://www.w3.org/2001/XMLSchema#
n9	http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n4	http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n13	http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n11	http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n5	http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item

n2:RIV%2F00216224%3A14310%2F03%3A00009270%21RIV08-MSM-14310___

rdf:type

skos:Concept n17:Vysledek

dcterms:description

Hinge-like RNA motifs occur at conserved positions in the 16S and 23S ribosomal RNAs, as revealed by x-ray crystallography of the 50S subunits of H. marismortui and D. radiodurans and the 30S subunit of T. thermophilus. The conformation of these asymmetric internal loops, called Kink-turns or K-turns, produces sharp, 120-degree bends in both phosphodiester backbones resulting in a V-shaped structure with an acute angle of ca.60 deg. between the RNA helices flanking the motif. In addition, some K-turns are specific binding sites for ribosomal proteins and take part in RNA-RNA tertiary interactions. We have carried out a set of explicit-solvent Molecular Dynamics (MD) simulations for selected K-turn motifs, including K-turn 38, and K-turn 42, and K-turn 58 from the 23S ribosomal RNA of Haloarcula marismortui. The simulations reveal an unprecedented dynamical flexibility of the K-turns,indicating that these motifs function as very flexible internal loops linking rigid helix stems and capable regulating s Hinge-like RNA motifs occur at conserved positions in the 16S and 23S ribosomal RNAs, as revealed by x-ray crystallography of the 50S subunits of H. marismortui and D. radiodurans and the 30S subunit of T. thermophilus. The conformation of these asymmetric internal loops, called Kink-turns or K-turns, produces sharp, 120-degree bends in both phosphodiester backbones resulting in a V-shaped structure with an acute angle of ca.60 deg. between the RNA helices flanking the motif. In addition, some K-turns are specific binding sites for ribosomal proteins and take part in RNA-RNA tertiary interactions. We have carried out a set of explicit-solvent Molecular Dynamics (MD) simulations for selected K-turn motifs, including K-turn 38, and K-turn 42, and K-turn 58 from the 23S ribosomal RNA of Haloarcula marismortui. The simulations reveal an unprecedented dynamical flexibility of the K-turns,indicating that these motifs function as very flexible internal loops linking rigid helix stems and capable regulating s Hinge-like RNA motifs occur at conserved positions in the 16S and 23S ribosomal RNAs, as revealed by x-ray crystallography of the 50S subunits of H. marismortui and D. radiodurans and the 30S subunit of T. thermophilus. The conformation of these asymmetric internal loops, called Kink-turns or K-turns, produces sharp, 120-degree bends in both phosphodiester backbones resulting in a V-shaped structure with an acute angle of ca.60 deg. between the RNA helices flanking the motif. In addition, some K-turns are specific binding sites for ribosomal proteins and take part in RNA-RNA tertiary interactions. We have carried out a set of explicit-solvent Molecular Dynamics (MD) simulations for selected K-turn motifs, including K-turn 38, and K-turn 42, and K-turn 58 from the 23S ribosomal RNA of Haloarcula marismortui. The simulations reveal an unprecedented dynamical flexibility of the K-turns,indicating that these motifs function as very flexible internal loops linking rigid helix stems and capable regulating s

dcterms:title

Structure And Dynamics Of RNA K-Turn Motifs Structure And Dynamics Of RNA K-Turn Motifs Structure And Dynamics Of RNA K-Turn Motifs

skos:prefLabel

Structure And Dynamics Of RNA K-Turn Motifs Structure And Dynamics Of RNA K-Turn Motifs Structure And Dynamics Of RNA K-Turn Motifs

skos:notation

RIV/00216224:14310/03:00009270!RIV08-MSM-14310___

n3:strany

41-41

n3:aktivita

n4:P

n3:aktivity

P(LN00A016)

n3:dodaniDat

n5:2008

n3:domaciTvurceVysledku

n10:9031510 n10:7167830 n10:4347374 n10:3223779 n10:4585623

n3:druhVysledku

n11:D

n3:duvernostUdaju

n20:S

n3:entitaPredkladatele

n8:predkladatel

n3:idSjednocenehoVysledku

629232

n3:idVysledku

RIV/00216224:14310/03:00009270

n3:jazykVysledku

n9:eng

n3:klicovaSlova

Molecular dynamics; RNA flexibility; non-Watson-Crick basepair

n3:klicoveSlovo

n14:Molecular%20dynamics n14:non-Watson-Crick%20basepair n14:RNA%20flexibility

n3:kontrolniKodProRIV

[77E13B20F336]

n3:mistoKonaniAkce

Nove Hrady

n3:mistoVydani

Praha

n3:nazevZdroje

Workshop on Modeling Interactions in Biomolecules : Programme and Book of Abstract

n3:obor

n13:CF

n3:pocetDomacichTvurcuVysledku

5

n3:pocetTvurcuVysledku

6

n3:projekt

n16:LN00A016

n3:rokUplatneniVysledku

n5:2003

n3:tvurceVysledku

Šponer, Jiří Špačková, Naděžda Leontis, Neocles B. Réblová, Kamila Koča, Jaroslav Rázga, Filip

n3:typAkce

n15:WRD

n3:zahajeniAkce

2003-09-15+02:00

s:numberOfPages

1

n12:hasPublisher

Praha

n18:organizacniJednotka

14310