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Statements

Subject Item
n2:RIV%2F00216224%3A14310%2F01%3A00005069%21RIV08-MSM-14310___
rdf:type
n16:Vysledek skos:Concept
dcterms:description
We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found. We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found. We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found.
dcterms:title
The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence
skos:prefLabel
The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence
skos:notation
RIV/00216224:14310/01:00005069!RIV08-MSM-14310___
n3:strany
43
n3:aktivita
n14:P n14:Z
n3:aktivity
P(NF5991), P(NF6520), Z(MSM 111100001), Z(MSM 141100002)
n3:cisloPeriodika
1
n3:dodaniDat
n10:2008
n3:domaciTvurceVysledku
n7:3881652 n7:7876874 n7:5317185
n3:druhVysledku
n12:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
673960
n3:idVysledku
RIV/00216224:14310/01:00005069
n3:jazykVysledku
n13:eng
n3:klicovaSlova
TaqI A polymorphism; DRD2; ACE; M235T; Angiotensinogen; Metamphetamine dependence
n3:klicoveSlovo
n5:ACE n5:DRD2 n5:Metamphetamine%20dependence n5:Angiotensinogen n5:M235T n5:TaqI%20A%20polymorphism
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[F6A84AE193DC]
n3:nazevZdroje
Physiological Research
n3:obor
n11:ED
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n8:NF5991 n8:NF6520
n3:rokUplatneniVysledku
n10:2001
n3:svazekPeriodika
50
n3:tvurceVysledku
Zvolský, Petr Šerý, Omar Vymětalová, Veronika
n3:zamer
n17:MSM%20111100001 n17:MSM%20141100002
s:issn
0862-8408
s:numberOfPages
8
n15:organizacniJednotka
14310