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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F14%3A00076659%21RIV15-MSM-14110___
rdf:type
n9:Vysledek skos:Concept
dcterms:description
MicroRNAs (miRNA), short non-coding regulatory RNAs, are implicated in deregulation of critical pathways involved in multiple myeloma (MM) and extramedullary form of MM (EM). EM is a type of MM defined by the presence of extraskeletal plasma cells (PCs) infiltrates, either related to bone or present in soft tissue. EM Circulating miRNAs are highly stable and are both detectable and quantifiable in a range of accessible bio fluids, thus have the potential to be useful diagnostic biomarkers. We have identified a specific serum miRNA profile in patients with extramedullary disease and correlated it with clinically important parameters. MicroRNAs (miRNA), short non-coding regulatory RNAs, are implicated in deregulation of critical pathways involved in multiple myeloma (MM) and extramedullary form of MM (EM). EM is a type of MM defined by the presence of extraskeletal plasma cells (PCs) infiltrates, either related to bone or present in soft tissue. EM Circulating miRNAs are highly stable and are both detectable and quantifiable in a range of accessible bio fluids, thus have the potential to be useful diagnostic biomarkers. We have identified a specific serum miRNA profile in patients with extramedullary disease and correlated it with clinically important parameters.
dcterms:title
CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE
skos:prefLabel
CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE CIRCULATING MIR-34a AND MIR-130a AS BIOMARKERS OF EXTRAMEDULLARY DISEASE
skos:notation
RIV/00216224:14110/14:00076659!RIV15-MSM-14110___
n3:aktivita
n15:P
n3:aktivity
P(EE2.3.20.0046)
n3:dodaniDat
n10:2015
n3:domaciTvurceVysledku
n6:1753142 n6:9450904 n6:3365891 n6:5132606 n6:9622748 n6:7861370
n3:druhVysledku
n17:O
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
7321
n3:idVysledku
RIV/00216224:14110/14:00076659
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Multiple myeloma; Quantitative RT-PCR
n3:klicoveSlovo
n4:Quantitative%20RT-PCR n4:Multiple%20myeloma
n3:kontrolniKodProRIV
[09687A38AEF1]
n3:obor
n11:FD
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
10
n3:projekt
n14:EE2.3.20.0046
n3:rokUplatneniVysledku
n10:2014
n3:tvurceVysledku
Hájek, Roman Adam, Zdeněk Kryukov, Fedor Sedlaříková, Lenka Ševčíková, Sabina Nekvindová, Jana Radová, Lenka Pour, Luděk Vrábel, Dávid Bešše, Lenka
n7:organizacniJednotka
14110