This HTML5 document contains 43 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n15http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14110%2F14%3A00076563%21RIV15-MSM-14110___/
dctermshttp://purl.org/dc/terms/
n14http://localhost/temp/predkladatel/
n17http://linked.opendata.cz/resource/domain/vavai/projekt/
n11http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n18http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
n4http://linked.opendata.cz/ontology/domain/vavai/riv/
skoshttp://www.w3.org/2004/02/skos/core#
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n8http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n13http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n6http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F14%3A00076563%21RIV15-MSM-14110___
rdf:type
skos:Concept n18:Vysledek
dcterms:description
Metabolic syndrome, a condition increasing cardiovascular morbidity, mortality and risk for diabetes mellitus type 2, is currently worldwide reaching epidemic proportions. This complex disorder represents an urgent challenge for new pharmacotherapeutic strategies formulation. Pathophysiological mechanisms underlying metabolic syndrome are not completely understood, nevertheless growing evidence is supporting the hypothesis that multiple metabolic dysregulations do contribute to its development. A potential target for pharmacological intervention is considered to be dysregulation of adipose tissue endocrine/paracrine function. Specific adipokines, proteins secreted by the adipose tissue, with some pleiotropic effects, have been identified with strong association to regulation of energy metabolism, appetite, insulin signaling, tissue insulin sensitivity and the proinflammatory state related to metabolic syndrome. Metabolic syndrome, a condition increasing cardiovascular morbidity, mortality and risk for diabetes mellitus type 2, is currently worldwide reaching epidemic proportions. This complex disorder represents an urgent challenge for new pharmacotherapeutic strategies formulation. Pathophysiological mechanisms underlying metabolic syndrome are not completely understood, nevertheless growing evidence is supporting the hypothesis that multiple metabolic dysregulations do contribute to its development. A potential target for pharmacological intervention is considered to be dysregulation of adipose tissue endocrine/paracrine function. Specific adipokines, proteins secreted by the adipose tissue, with some pleiotropic effects, have been identified with strong association to regulation of energy metabolism, appetite, insulin signaling, tissue insulin sensitivity and the proinflammatory state related to metabolic syndrome.
dcterms:title
Metabolic syndrome – dysregulation of adipose tissue endocrine function Metabolic syndrome – dysregulation of adipose tissue endocrine function
skos:prefLabel
Metabolic syndrome – dysregulation of adipose tissue endocrine function Metabolic syndrome – dysregulation of adipose tissue endocrine function
skos:notation
RIV/00216224:14110/14:00076563!RIV15-MSM-14110___
n4:aktivita
n9:V n9:S n9:P
n4:aktivity
P(ED1.1.00/02.0068), S, V
n4:cisloPeriodika
4
n4:dodaniDat
n6:2015
n4:domaciTvurceVysledku
n11:2512866
n4:druhVysledku
n13:J
n4:duvernostUdaju
n10:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
28528
n4:idVysledku
RIV/00216224:14110/14:00076563
n4:jazykVysledku
n16:eng
n4:klicovaSlova
metabolic syndrome; insulin resistance; adipose tissue; adipokines
n4:klicoveSlovo
n8:adipokines n8:adipose%20tissue n8:insulin%20resistance n8:metabolic%20syndrome
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[B160E37872EA]
n4:nazevZdroje
Česká a slovenská farmacie
n4:obor
n7:FR
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
4
n4:projekt
n17:ED1.1.00%2F02.0068
n4:rokUplatneniVysledku
n6:2014
n4:svazekPeriodika
63
n4:tvurceVysledku
Suchý, Pavel Kučerová, Jana Kotolová, Hana Horská, Kateřina
s:issn
1210-7816
s:numberOfPages
8
n14:organizacniJednotka
14110