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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F14%3A00076462%21RIV15-MSM-14110___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
BACKGROUND AND PURPOSEThe basal ganglia and the cerebellum have both emerged as important structures involved in the processing of temporal information. METHODSWe examined the roles of the cerebellum and striatum in predictive motor timing during a target interception task in healthy individuals (HC group; n = 21) and in patients with early Parkinson's disease (early stage PD group; n = 20) using functional magnetic resonance imaging. RESULTSDespite having similar hit ratios, the PD failed more often than the HC to postpone their actions until the right moment and to adapt their behavior from one trial to the next. We found more activation in the right cerebellar lobule VI in HC than in early stage PD during successful trials. Successful trial-by-trial adjustments were associated with higher activity in the right putamen and lobule VI of the cerebellum in HC. CONCLUSIONSWe conclude that both the cerebellum and striatum are involved in predictive motor timing tasks. BACKGROUND AND PURPOSEThe basal ganglia and the cerebellum have both emerged as important structures involved in the processing of temporal information. METHODSWe examined the roles of the cerebellum and striatum in predictive motor timing during a target interception task in healthy individuals (HC group; n = 21) and in patients with early Parkinson's disease (early stage PD group; n = 20) using functional magnetic resonance imaging. RESULTSDespite having similar hit ratios, the PD failed more often than the HC to postpone their actions until the right moment and to adapt their behavior from one trial to the next. We found more activation in the right cerebellar lobule VI in HC than in early stage PD during successful trials. Successful trial-by-trial adjustments were associated with higher activity in the right putamen and lobule VI of the cerebellum in HC. CONCLUSIONSWe conclude that both the cerebellum and striatum are involved in predictive motor timing tasks.
dcterms:title
Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease
skos:prefLabel
Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease Functional Imaging of the Cerebellum and Basal Ganglia During Predictive Motor Timing in Early Parkinson's Disease
skos:notation
RIV/00216224:14110/14:00076462!RIV15-MSM-14110___
n4:aktivita
n15:Z n15:P
n4:aktivity
P(ED1.1.00/02.0068), Z(MSM0021622404)
n4:cisloPeriodika
1
n4:dodaniDat
n10:2015
n4:domaciTvurceVysledku
n11:2673517 n11:3561119 n11:7325401 n11:6185134
n4:druhVysledku
n17:J
n4:duvernostUdaju
n14:S
n4:entitaPredkladatele
n18:predkladatel
n4:idSjednocenehoVysledku
17659
n4:idVysledku
RIV/00216224:14110/14:00076462
n4:jazykVysledku
n6:eng
n4:klicovaSlova
Basal ganglia; cerebellum; fMRI; Parkinson's disease; prediction; timing
n4:klicoveSlovo
n13:Parkinson%27s%20disease n13:prediction n13:cerebellum n13:fMRI n13:timing n13:Basal%20ganglia
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[C38E0E93F709]
n4:nazevZdroje
Journal of Neuroimaging
n4:obor
n19:FH
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
7
n4:projekt
n8:ED1.1.00%2F02.0068
n4:rokUplatneniVysledku
n10:2014
n4:svazekPeriodika
24
n4:tvurceVysledku
Lungu, Ovidiu V Gescheidt, Tomáš Bareš, Martin Krupa, Petr Mareček, Radek Čechová, Ivica Mikl, Michal
n4:wos
000329509100008
n4:zamer
n20:MSM0021622404
s:issn
1051-2284
s:numberOfPages
9
n9:doi
10.1111/j.1552-6569.2011.00663.x
n16:organizacniJednotka
14110