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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F14%3A00074222%21RIV15-MSM-14110___
rdf:type
skos:Concept n20:Vysledek
dcterms:description
An infrequent change to an otherwise repetitive sequence of stimuli leads to the generation of mismatch negativity (MMN), even in the absence of attention. This evoked negative response occurs in the scalp-recorded electroencephalogram (EEG) over the temporal and frontal cortices, 100–250 ms after onset of the deviant stimulus. The MMN is used to detect sensory information processing. The aim of our study was to investigate whether MMN can be recorded in the subthalamic nuclei (STN) as evidence of auditory information processing on an unconscious level within this structure. To our knowledge, MMN has never been recorded in the human STN. We recorded intracerebral EEG using a MMN paradigm in five patients with Parkinson’s disease (PD) who were implanted with depth electrodes in the subthalamic nuclei (STN). We found far-field MMN when intracerebral contacts were connected to an extracranial reference electrode. An infrequent change to an otherwise repetitive sequence of stimuli leads to the generation of mismatch negativity (MMN), even in the absence of attention. This evoked negative response occurs in the scalp-recorded electroencephalogram (EEG) over the temporal and frontal cortices, 100–250 ms after onset of the deviant stimulus. The MMN is used to detect sensory information processing. The aim of our study was to investigate whether MMN can be recorded in the subthalamic nuclei (STN) as evidence of auditory information processing on an unconscious level within this structure. To our knowledge, MMN has never been recorded in the human STN. We recorded intracerebral EEG using a MMN paradigm in five patients with Parkinson’s disease (PD) who were implanted with depth electrodes in the subthalamic nuclei (STN). We found far-field MMN when intracerebral contacts were connected to an extracranial reference electrode.
dcterms:title
Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients
skos:prefLabel
Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients Mismatch negativity-like potential (MMN-like) in the subthalamic nuclei in Parkinson’s disease patients
skos:notation
RIV/00216224:14110/14:00074222!RIV15-MSM-14110___
n3:aktivita
n13:Z n13:P n13:I
n3:aktivity
I, P(ED0017/01/01), P(ED1.1.00/02.0068), P(ED1.100/02/0123), P(GAP103/11/0933), P(LO1212), Z(MSM0021622404)
n3:cisloPeriodika
12
n3:dodaniDat
n10:2015
n3:domaciTvurceVysledku
n4:1791656 n4:7495617 n4:2673517 n4:2594765 Shaw, Daniel Joel
n3:druhVysledku
n15:J
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
29521
n3:idVysledku
RIV/00216224:14110/14:00074222
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Intracranial electrodes; Mismatch negativity; MMN; MMN-like; STN; Subthalamic nucleus
n3:klicoveSlovo
n8:Subthalamic%20nucleus n8:Intracranial%20electrodes n8:Mismatch%20negativity n8:MMN-like n8:STN n8:MMN
n3:kodStatuVydavatele
AT - Rakouská republika
n3:kontrolniKodProRIV
[C382254F71D9]
n3:nazevZdroje
Journal of Neural Transmission
n3:obor
n9:FH
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:projekt
n14:ED0017%2F01%2F01 n14:GAP103%2F11%2F0933 n14:ED1.1.00%2F02.0068 n14:LO1212 n14:ED1.100%2F02%2F0123
n3:rokUplatneniVysledku
n10:2014
n3:svazekPeriodika
121
n3:tvurceVysledku
Jurák, Pavel Chrastina, Jan Halámek, Josef Bareš, Martin Shaw, Daniel Joel Minks, Eduard Chládek, Jan
n3:wos
000345409000005
n3:zamer
n17:MSM0021622404
s:issn
0300-9564
s:numberOfPages
16
n19:doi
10.1007/s00702-014-1221-3
n18:organizacniJednotka
14110