This HTML5 document contains 43 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n11http://localhost/temp/predkladatel/
n8http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F00216224%3A14110%2F12%3A00063764%21RIV13-MSM-14110___/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n13http://linked.opendata.cz/resource/domain/vavai/subjekt/
n12http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n4http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n7http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n10http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F12%3A00063764%21RIV13-MSM-14110___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
The prevailing aerobic glycolysis (so called Warburg effect) in cancer cells is according to current understanding the consequence of reprogramming of cellular metabolism during the process of malignant transformation. Metabolic regulation is inseparable component of cell proliferation machinery and has a tight link with activities of oncogenes and suppressor genes. The purpose of metabolic reprogramming of cancer (but also normal intensively proliferating cells) cells is to incorporate greater fraction of glucose metabolites into newly synthesised macromolecules. Apart from that, aerobic glycolysis confers several other selective advantages to cancer cells. Epidemiological data indicate that type 2 diabetes mellitus is associated increased incidence of several types of cancer and that cancer mortality can be influenced by certain types of anti-diabetic treatment, however future research is needed to explain whether this relationship might be causal. The prevailing aerobic glycolysis (so called Warburg effect) in cancer cells is according to current understanding the consequence of reprogramming of cellular metabolism during the process of malignant transformation. Metabolic regulation is inseparable component of cell proliferation machinery and has a tight link with activities of oncogenes and suppressor genes. The purpose of metabolic reprogramming of cancer (but also normal intensively proliferating cells) cells is to incorporate greater fraction of glucose metabolites into newly synthesised macromolecules. Apart from that, aerobic glycolysis confers several other selective advantages to cancer cells. Epidemiological data indicate that type 2 diabetes mellitus is associated increased incidence of several types of cancer and that cancer mortality can be influenced by certain types of anti-diabetic treatment, however future research is needed to explain whether this relationship might be causal.
dcterms:title
Cancer as a metabolic disease and diabetes as a cancer risk? Cancer as a metabolic disease and diabetes as a cancer risk?
skos:prefLabel
Cancer as a metabolic disease and diabetes as a cancer risk? Cancer as a metabolic disease and diabetes as a cancer risk?
skos:notation
RIV/00216224:14110/12:00063764!RIV13-MSM-14110___
n12:predkladatel
n13:orjk%3A14110
n3:aktivita
n18:O
n3:aktivity
O
n3:cisloPeriodika
Suppl. 2
n3:dodaniDat
n10:2013
n3:domaciTvurceVysledku
n6:7988788
n3:druhVysledku
n15:J
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
125907
n3:idVysledku
RIV/00216224:14110/12:00063764
n3:jazykVysledku
n16:eng
n3:klicovaSlova
diabetes; cancer; obesity; metabolism; glyoxalase; transketolase; p53; metformin
n3:klicoveSlovo
n4:obesity n4:glyoxalase n4:diabetes n4:metformin n4:metabolism n4:transketolase n4:p53 n4:cancer
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[0E3A1C22BBE6]
n3:nazevZdroje
Klinická onkologie
n3:obor
n17:FB
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:rokUplatneniVysledku
n10:2012
n3:svazekPeriodika
25
n3:tvurceVysledku
Hrstka, Roman Kaňková, Kateřina
s:issn
0862-495X
s:numberOfPages
6
n11:organizacniJednotka
14110