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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F12%3A00060425%21RIV13-MSM-14110___
rdf:type
n10:Vysledek skos:Concept
dcterms:description
Restenosis after percutaneous coronary intervention (PCI) represents a major limitation to this procedure and despite large efforts it is still difficult to stratify patients after PCI according to restenosis risk. A wide range of proteins have been investigated in order to establish new diagnostic/prognostic markers of restenosis after PCI, without major effects. Adiponectin, a protein secreted exclusively by the adipose tissue, has recently emerged as an anti-inflammatory, anti-atherogenic, insulin-sensitizing factor providing possible link between white adipose tissue and cardiovascular disease. This crucial role in cardioprotection is mediated via a variety of mechanisms, including inhibition of foam cell formation, expression of antithrombogenic properties and inhibition of smooth muscle cells proliferation, all vital processes in restenosis development. Considering its cardioprotective effects, the role of adiponectin in prediction of adverse cardiovascular events has been studied extensively. Restenosis after percutaneous coronary intervention (PCI) represents a major limitation to this procedure and despite large efforts it is still difficult to stratify patients after PCI according to restenosis risk. A wide range of proteins have been investigated in order to establish new diagnostic/prognostic markers of restenosis after PCI, without major effects. Adiponectin, a protein secreted exclusively by the adipose tissue, has recently emerged as an anti-inflammatory, anti-atherogenic, insulin-sensitizing factor providing possible link between white adipose tissue and cardiovascular disease. This crucial role in cardioprotection is mediated via a variety of mechanisms, including inhibition of foam cell formation, expression of antithrombogenic properties and inhibition of smooth muscle cells proliferation, all vital processes in restenosis development. Considering its cardioprotective effects, the role of adiponectin in prediction of adverse cardiovascular events has been studied extensively.
dcterms:title
Adiponectin, its cardioprotective effects and genetic variability in relation to restenosis after percutaneous coronary intervention (PCI) Adiponectin, its cardioprotective effects and genetic variability in relation to restenosis after percutaneous coronary intervention (PCI)
skos:prefLabel
Adiponectin, its cardioprotective effects and genetic variability in relation to restenosis after percutaneous coronary intervention (PCI) Adiponectin, its cardioprotective effects and genetic variability in relation to restenosis after percutaneous coronary intervention (PCI)
skos:notation
RIV/00216224:14110/12:00060425!RIV13-MSM-14110___
n10:predkladatel
n17:orjk%3A14110
n3:aktivita
n18:I
n3:aktivity
I
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n11:3973484 n11:9688498 n11:4447719
n3:druhVysledku
n14:C
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
121111
n3:idVysledku
RIV/00216224:14110/12:00060425
n3:jazykVysledku
n13:eng
n3:klicovaSlova
adiponectin; percutaneous coronary intervention; restenosis; polymorphism
n3:klicoveSlovo
n4:polymorphism n4:percutaneous%20coronary%20intervention n4:restenosis n4:adiponectin
n3:kontrolniKodProRIV
[6E594FCBD69B]
n3:mistoVydani
New York
n3:nazevEdiceCisloSvazku
Endocrinology Research and Clinical Developments
n3:nazevZdroje
Adiponectin: Production, Regulation and Roles in Disease
n3:obor
n20:FA
n3:pocetDomacichTvurcuVysledku
3
n3:pocetStranKnihy
180
n3:pocetTvurcuVysledku
3
n3:rokUplatneniVysledku
n7:2012
n3:tvurceVysledku
Bienert, Petr Vašků, Anna Bienertová Vašků, Julie
s:numberOfPages
16
n12:hasPublisher
Nova Science Publishers
n19:isbn
9781619421653
n6:organizacniJednotka
14110