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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F11%3A00056980%21RIV12-MZ0-14110___
rdf:type
skos:Concept n15:Vysledek
dcterms:description
To determine intraindividual variability in concentrations of homocysteine and related thiols in follicular fluids of particular follicles after ovarian stimulation and assess the differences between follicles with/or without oocytes. Methods HPLC-FD analysis of plasma and follicular fluid cysteine, homocysteine, cysteinylglycine and glutathione in women undergoing IVF. In blood plasma, the homocysteine, cysteine, and cysteinylglycine concentrations decreased significantly during stimulation with rec FSH (p<0.001). We found significant differences in concentrations of cysteine and glutathione between follicles with or without retrieved oocytes. High intraindividual variability in concentrations of thiols was determined. The concentration variability of thiols between single follicles is very high and we recommend mean at least from 3 follicles with/or without oocytes for characterization of each woman. To determine intraindividual variability in concentrations of homocysteine and related thiols in follicular fluids of particular follicles after ovarian stimulation and assess the differences between follicles with/or without oocytes. Methods HPLC-FD analysis of plasma and follicular fluid cysteine, homocysteine, cysteinylglycine and glutathione in women undergoing IVF. In blood plasma, the homocysteine, cysteine, and cysteinylglycine concentrations decreased significantly during stimulation with rec FSH (p<0.001). We found significant differences in concentrations of cysteine and glutathione between follicles with or without retrieved oocytes. High intraindividual variability in concentrations of thiols was determined. The concentration variability of thiols between single follicles is very high and we recommend mean at least from 3 follicles with/or without oocytes for characterization of each woman.
dcterms:title
Intraindividual variability of homocysteine and related thiols concentrations in follicular fluid Intraindividual variability of homocysteine and related thiols concentrations in follicular fluid
skos:prefLabel
Intraindividual variability of homocysteine and related thiols concentrations in follicular fluid Intraindividual variability of homocysteine and related thiols concentrations in follicular fluid
skos:notation
RIV/00216224:14110/11:00056980!RIV12-MZ0-14110___
n15:predkladatel
n18:orjk%3A14110
n3:aktivita
n13:P
n3:aktivity
P(NS9661)
n3:cisloPeriodika
9
n3:dodaniDat
n7:2012
n3:domaciTvurceVysledku
n4:4222229 n4:1241184 n4:3657183 n4:9478426 n4:9456384 n4:4182952 n4:7982186
n3:druhVysledku
n17:J
n3:duvernostUdaju
n10:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
205557
n3:idVysledku
RIV/00216224:14110/11:00056980
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Homocysteine; Thiols; Follicular fluid; Oocytes
n3:klicoveSlovo
n5:Oocytes n5:Thiols n5:Follicular%20fluid n5:Homocysteine
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[972184D43212]
n3:nazevZdroje
Journal of Assisted Reproduction and Genetics
n3:obor
n11:FK
n3:pocetDomacichTvurcuVysledku
7
n3:pocetTvurcuVysledku
7
n3:projekt
n9:NS9661
n3:rokUplatneniVysledku
n7:2011
n3:svazekPeriodika
28
n3:tvurceVysledku
Králíková, Michaela Tallová, Jaroslava Jarkovský, Jiří Žáková, Jana Matejovičová, Milena Crha, Igor Melounová, Jitka
n3:wos
000294808400014
s:issn
1058-0468
s:numberOfPages
6
n20:doi
10.1007/s10815-011-9606-9
n14:organizacniJednotka
14110