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Statements

Subject Item
n2:RIV%2F00216224%3A14110%2F11%3A00053566%21RIV12-MSM-14110___
rdf:type
n11:Vysledek skos:Concept
dcterms:description
Myocardial ischemia-reperfusion injury is linked with production of oxygen free radicals. We evaluated the production of hydroxyl radical in isolated guinea pig hearts during ischemia and reperfusion. To investigate the other parameters of myocardial injury, we measured the creatine kinase, lactate dehydrogenase and lactate in collected effluents during both ischemia and reperfusion periods. The increased levels of CK, LDH and lactate and the comparison of these parameters with production of hydroxyl radicals shows that the hydroxyl radicals generation play important role in ischemia-reperfusion injury. Myocardial ischemia-reperfusion injury is linked with production of oxygen free radicals. We evaluated the production of hydroxyl radical in isolated guinea pig hearts during ischemia and reperfusion. To investigate the other parameters of myocardial injury, we measured the creatine kinase, lactate dehydrogenase and lactate in collected effluents during both ischemia and reperfusion periods. The increased levels of CK, LDH and lactate and the comparison of these parameters with production of hydroxyl radicals shows that the hydroxyl radicals generation play important role in ischemia-reperfusion injury.
dcterms:title
In vivo determination of hydroxyl radicals in isolated guinea pig hearts during ischemia and reperfusion In vivo determination of hydroxyl radicals in isolated guinea pig hearts during ischemia and reperfusion
skos:prefLabel
In vivo determination of hydroxyl radicals in isolated guinea pig hearts during ischemia and reperfusion In vivo determination of hydroxyl radicals in isolated guinea pig hearts during ischemia and reperfusion
skos:notation
RIV/00216224:14110/11:00053566!RIV12-MSM-14110___
n11:predkladatel
n12:orjk%3A14110
n3:aktivita
n17:Z
n3:aktivity
Z(MSM0021622402)
n3:dodaniDat
n16:2012
n3:domaciTvurceVysledku
n13:1469517 n13:4078624 n13:3682455 n13:7045182
n3:druhVysledku
n4:O
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n5:predkladatel
n3:idSjednocenehoVysledku
204057
n3:idVysledku
RIV/00216224:14110/11:00053566
n3:jazykVysledku
n14:eng
n3:klicovaSlova
isolated heart; guinea pig; hydroxyl radical; CK; LDH
n3:klicoveSlovo
n6:hydroxyl%20radical n6:isolated%20heart n6:LDH n6:guinea%20pig n6:CK
n3:kontrolniKodProRIV
[E77ED94F6789]
n3:obor
n15:CE
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n16:2011
n3:tvurceVysledku
Nováková, Marie Paulová, Hana Stračina, Tibor Táborská, Eva
n3:zamer
n7:MSM0021622402
n10:organizacniJednotka
14110